Bordetella Pertussis Flashcards

Flashcards about Bordetella Pertussis

Bordetella

A family of microorganisms that cause disease in animals.

Pertussis

Another name for whooping cough.

Parapertussis

A milder infection compared to pertussis.

Bronchioles

The part of the respiratory system that is predominantly affected in severe pertussis.

Laryngitis or Bronchitis

In adults, Bordetella pertussis predominantly causes this, resulting in a chronic nagging cough.

Coccobacillus

The Gram stain morphology of Bordetella pertussis.

Selective Media

A type of media used to grow Bordetella pertussis.

Five Days

The amount of time it takes to grow Bordetella pertussis.

Bordet-Gengou Medium

A selective medium used for growing Bordetella pertussis.

Bisected Pearls

The description of Bordetella pertussis colonies grown on Bordet-Gengou medium.

Catarrhal Stage

The stage of pertussis in which the organism is most infectious.

Secondary Attack Rate

A statistic that describes how easily pertussis is transmitted to individuals in close proximity.

Children Under Two Months

The age group at greatest risk of death from pertussis.

Severe Coughing

The main symptom of pertussis in young infants.

Pathogenesis

The process by which Bordetella pertussis destroys ciliated cells.

Inhibition

The effect of Bordetella pertussis on mucus clearance.

Modulate Host Immunity

The ability of Bordetella pertussis to change the body's immune response.

Surfactant A (SPA)

A surfactant that is not recognized by lipo-oligosaccharide, which normally controls respiratory infections.

Lipo-oligosaccharide (LOS)

A component of gram-negative bacteria that inhibits complement.

Plugs of Necrotic Material

The result of necrosis in the bronchioles that interferes with oxygen exchange.

Filamentous Hemagglutinin

A factor on Bordetella pertussis that is important for adhesion.

Fimbriae

Small, hair-like appendages on the surface of bacteria important for adhesion.

Pertactin

A factor that assists in cell wall adhesion and invasion.

Adenylate Cyclase Toxin

A toxin that interferes with internal cytoplasmic processes.

BTEA

A toxin that is injected through a type three secretion system.

Pertussis Toxin (PT Toxin)

A toxin that is not found in parapertussis.

B (Binding) Part

The part of the pertussis toxin that is responsible for binding to host cells.

Lymphocyte-Derived Immunity

The type of immunity that is not well-developed in pertussis infections.

Poor IgG Production

The problem associated with serological diagnosis of pertussis due to the bacteria's ability.

Within the First Two Weeks

The recommendation for nasopharyngeal specimens for culture.

Azithromycin or Erythromycin

Antibiotics used to treat pertussis in infants and young children.

Penicillin

An antibiotic that does not work well on Bordetella.

Vaccination

The most important mainstay for preventing pertussis.

Around Five Years

The biggest problem with the pertussis vaccine is the duration of protection, which is this long.

Acellular Vaccine

The type of pertussis vaccine currently in use.

filamentous hemagglutinin

A protein on the surface of Bordetella pertussis that promotes attachment to host cells.

Type Three Secretion System

The system Bordetella pertussis uses to inject toxins into host cells.

Reactive Oxygen Species

A result of cell damage that can lead to cellular death and cyanotoxicity.

IgG

Pertussis is very good at reducing the production of this antibody.

Treatment

If this can be started early, it's better when dealing with pertussis.