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the integumentary system
comprised of the skin, hair, and nails
skin
largest organ of the body, made up of the epidermis, dermis, and hypodermis
epidermis
outer layer, made of stratified squamous epithelium, avascular (no direct blood flow), recieves nutrients from the basement membrane
four layers of the epidermis
stratum corneum, stratum granulosum, stratum spinosum, and stratum basale
stratum basale
bottom layer of the epidermis, adhered to the basement membrane, constantly dividing to rebuild the skin
epidermal ridges
formed by the stratum basale, also called fingerprints, are unique to each person and consistent through life
cells found in the epidermis
keratinocytes, Langerhans cells, fibroblast cells, melanocytes, and Merkel cells
langerhans cells
act as a first lie of defense, identifying microorganisms before reaching the bloodstream
merkel cells
sensory receptor that responds to light tough
fibroblast cells
produce collagen which adheres the epidermis cells together and give the skin elasticity, supports the tissue matrix of wounds until new cells are developed
dermis
middle layer, contains sweat glands, oil glands, and sensory organs, has a high water content
papillary region
superficial layer of the dermis, contains collagen fibers and elastic fibers
reticular region
deep layer of the dermis, contains collagen fibers and elastic fibers, contains the skins main blood supply
contusion
a bruise, damage of a blood vessel in the skin
hypodermis
inner layer, also called subcutaneous, made of mostly fat cells (adipocytes), anchors the dermis to a layer of fat cells
skin cells
absorb ultraviolet light to produce vitamin D, contains sensory receptors and glands for protection from pathogenic microorganisms and temp changes
lymphatic system
protects the body is foreign objects and microbes that get into the body due to integumentary system damage
merkels cells and meissners corpuscles
mechanoreceptors that detect sensory info by way of light touch and vibration
nociceptors
detect pain, like from a pin prick
pacinian corpuscles
detect mechanical sensory info based on pressure applied to the skin
thermoreceptors
detect hot and cold
exocrine glands
release secretions through a duct into an epithelial surface or lining
multicellular glands
set within epithelial tissue and release contents through a duct to the surface
sebaceous glands
(oil glands) produce sebum to keep the hair and skin from drying out and inhibits the growth of harmful microorganisms
sweat glands
(sudoriferous glands) produce sweat in almost every part of the skin
dermatome
a region of skin innervated by one sensory nerve, sends sensory nerves to the spinal nerve, then the spinal cord, then other the brain for processing
hair
made up of dead epidermal cells that have been converted to keratin
hair root
begins at the hair bulb which has a blood and nervous supply in the dermis
hair shaft
extends through the epidermis to the outside
arrector pili muscle
a smooth muscle on each hair follicle that contracts when the body is cold or experiences emotional responses
nails
composed of dead epidermal cells that have been converted to keratin
nail body
visible portion of the nail, covering the epidermis called the nail bed
cuticle
the stratum corneum of the epidermis that extends from the nail root, covering some of the visible portion of the nail
lunula
visible portion of the nail bed near the nail root
tissues
cells that come together, comprised of cells and a matrix
matrix
(extracellular material) made up of ground substance, protein, and collagen
clot
blood platelets accumulate at the damage site to form a mesh like substance and prevent blood loss
mast cells
release histamine to dilate blood vessels to bring more blood and nutrients to the damage site, initiate an inflammatory response
macrophages
engulf and destroy disease-causing pathogens
scar
an overgrowth of the fibrous connective tissue that cannot be fully replaced, caused when the wound is too deep, some of the original function is lost
first degree burn
only damage the epidermis, becomes dry, red, and painful, eg: sunburn
second degree burn
damages the epidermis and some of the dermis, turns red and forms blister, is painful and swollen due to damage to the sensory organs in the dermis
third degree burn
damage the epidermis, dermis, and possibly the subcutaneous layer, typically becomes white and possible “charred”, extremely painful
fourth degree burn
damages the epidermis, dermis, hypodermis, and some of the tissue such as a muscle or bone, no sensation due to destroyed nerve endings, may require a skin graft