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Flashcards covering concepts related to respiratory function and gas exchange from lecture notes.
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Parts of the upper airway
Nasopharynx, oropharynx, laryngopharynx
Structures of the lower airway
Larynx, trachea, bronchi, bronchioles, alveoli
Function of the nasal cavity
Filters, warms, and humidifies air
Vibrissae
Large hairs that filter air in the nose
Role of cilia
Move mucus and trapped particles upward
Type of epithelium lining the trachea
Pseudostratified ciliated columnar epithelium
Location of gas exchange
Alveoli
Type I alveolar cells
Cells involved in gas exchange
Type II alveolar cells
Cells that produce surfactant
Function of alveolar macrophages
Remove debris and pathogens
Anatomic dead space
Air not used in gas exchange
Alveolar dead space
Ventilated but not perfused alveoli
Physiologic dead space
Anatomic + alveolar dead space
Process during inspiration
Diaphragm contracts, pressure decreases, air flows in
Process during expiration
Lungs recoil and air flows out passively
Surfactant
Substance that reduces surface tension in alveoli
Importance of surfactant
Prevents alveolar collapse
Airway resistance
Resistance to airflow in the respiratory tract
Factors increasing airway resistance
Mucus, bronchospasm, decreased radius
Location of highest airway resistance
Nose
Location of lowest airway resistance
Small bronchioles
Lung compliance
Ease of lung expansion
Factors decreasing lung compliance
Aging, fibrosis, chest wall rigidity
Factors increasing lung compliance
Loss of elastic tissue
Neurological control of breathing
Pons and medulla
Pneumotaxic center
Controls breathing rate and ends inspiration
Response of central chemoreceptors
CO2 and pH changes
Response of peripheral chemoreceptors
Low oxygen levels
Hypoventilation
Insufficient air reaching alveoli
Effect of hypoventilation
High CO2 and low oxygen
Hyperventilation
Excessive ventilation causing low CO2
Causes of hypoventilation
Drugs, obesity, muscle weakness
Causes of hyperventilation
Anxiety, fever, high altitude
Function of bronchial arteries
Supply oxygenated blood to lung tissue
Function of pulmonary arteries
Carry deoxygenated blood for gas exchange
Effect of hyperventilation on CO2 levels
They decrease
Effect of low CO2 on oxygen binding
Oxygen binds more tightly to hemoglobin
Affects on distribution of ventilation
Body position
Location of greatest ventilation in upright lung
At the base
Effect of smoking on ciliary function
It is impaired.