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Metabolism
All chemical reactions that take place in an organism
Metabolic reactions do 2 things
Extract enrgy from nutrient biomolecules
Synthesize or break down molecules
Metabolism
Usefulness of metabolic pathways as supplilers of energy is measured in terms of the new amount of ATP the pathways can yield
Aerobic metabolism
One glucose molecule yields 30-32 ATP
Process requires the presence of oxygen
Anaerobic Metabolism
Once glucose molecule yields 2 ATP
Process doesn't require the presence of oxygen
Energy
The capacity or ability to perform work
All living organisms obtain, store and use energy to fuel their activities
Power
The rate of change of energy, or how quickly you can perform work
Power output is the rate at which working muscles can produce energy
Adenosine triphosphate (ATP)
3 phophate groups
Attached to adenosine
Immediate energy source for muscle contractions
The phosphate bonds release energy when they are broken
ATP is broken down into ADP and a phosphate group and then resynthesize
Take energy to resynthesize ATP
Aerobic metabolism
A metabolic process that yields 36 ATP per 2 glucose molecule and requires oxygen.
Anaerobic metabolism
A metabolic process that yields 2 ATP per glucose molecule and does not require oxygen.
Phosphagen system
ATP-Creatine-Phosphate System (ATP-PC-System)
The immediate energy system
Imperative for activities with high power outputs
ATP is broken down into Adenosine Diphosphate and inorganic phosphate (ADP and Phosphate) and releases energy. Uses ATPase an enzyme
ATP is being resynthesized by the energy released when the chemical bonds of creatine-phosphate are broken. Uses Creatine kinase as enzyme
Coupled reaction
Coupled reaction
A process where the energy released by one chemical reaction drives another chemical reaction. Energy released by creatine and phosphate’s bond breaking is used to reform ATP from ADP and P
Anaerobic Glycolysis
Anaerobic Glycolysis (no oxygen)
Requires the chemical breakdown of glycogen or glucose
Availability of glucose occurs through 2 methods
Glucose can pass from blood through muscle cell membrane into the cell, Net of 2 ATP
Glucose sprints from stored glycogen in the muscle cell itself, Net of 3 ATP
Will produce Lactate (not lactic acid)
It processes ATP quickly during exercise when oxygen demand is greater than supply
High rates of ATP production by glycolysis can't be sustained for long
60-90 seconds
Local muscle fatigue is typically the result of exhausting this path way
Low muscle pH is associated with hydrogen concentration and lactate formation
High acidity is believed to contribute to the acute muscular discomfort experienced during intense exercise (local muscle fatigue)
Lactate gets resynthesized into glucose again in the liver
Oxidative system
Requires the presence of oxygen
Predominantly used in everyday activities where intensity is lower and longer in duration, more than 2-3 minutes
Chemical breakdown of carbs, fatrs and proteins
Carbohydrate
4kcal/g
Fat
9kcal/g
Protein
4kcal/g
EPOC, Excessive post-exercise comsumption
Uptake of oxygen after exercise that is higher than during typical resting states
Muscle phosphagen stores (ATP and CP) are replenishing and the oxygen that is carried in blood and muscle
Rapid recovery phase
Body temp can remain elevated for a long time after the cessation of strenuous exercise
This increases the rate of chemical reactions in the cells of the body
Slower recovery phase
Residual effects or hormones released during exercise like epinephrine and thyronine and will continue to increase metabolism during recovery until they dissipate
Energy is needed for tissue repair and redistribution of ions (sodium, potassium, calcium) in the body
Since heart rate and breathing rate remain elevated during recovery, the extra oxygen is needed for the heart and respiratory muscles
Active vs Passive Recovery
The return of muscle acidity to normal levels is accelerated by active aerobic recovery exercise
Active recover speeds up the rate of blood flow throughout the muscle, normalizing muscle acidity faster
Fatigue and Exercise
Inability to maintain your desired exercise intensity
Training above LT1
Fatigue is likely cause of the depletion of msucle glycogen
Train close to L2
Fatigue is likely due to the inability to continue to buffer high muscle acidity at the required rate
Not able to control muscle acidity
Training above LT2
Fatigue occur quickly cause of high muscle acidity, reducing ATP production through glycolysis
Lactate
A by-product of anaerobic metabolism often viewed as a source of fuel and does not directly cause fatigue.
Central Nervous System (CNS) fatigue
During intense repeated bout of strenuous exercise neurotransmitters get deplete and reduces physically and cognitive performance
Muscular fatigue from the CNS results in a reduction in the neural drive to working muscles
Will decrease in force output
Peripheral weakness manifests as a local, muscle-specific incapacity to do work
Peak Power with Phosphagen System
Peak power
Used in activates that only take a few seconds or less
10 seconds or less, primarily relies on stored ATP
1 max jump
Sustained power
Used in activities that required high power outputs for several seconds
Primarily relies on ATP-CP system
Long jump, 60-100m sprint
Glycolytic System Breakdown
Glucose turns into 2 pyruvate than into 2 lactate. The lactate is then resynthesized into glucose in the liver
Oxidative System Breakdown
Glucose turns into pyruvate and then into Acetyl Co-A as it enters the mitochondria. The citric Acid Cycle occurs in the mitochondria and CO2 are produced. Hydrogen ions and high energy electrons are removed from carbon atoms and move into the electron transport system. They combine with oxygen to form water and ATP.
This creates a total of 38 ATP, 2 ATP from turning into pyruvate and 36 after the electron transport system
Oxidation of Fats
Aerobic lipolysis
Fatty acids are released from adipose tissue and used to make ATP
Fat is the ideal way for our bodies to story energy since its so energy dense. 1g of fat if 9kcal
occurs when we exercise for incredibly long periods of time like 3-4 hours
Oxidation of Fat Breakdown
Fat to fatty acids than goes through beta oxidation to turn into acetyl Co-A. This then goes into the citric Acid cycle, a hydrogen ion and high energy electron enters the electron transport system to turn into O2 and ATP
Protein Metabolism
Least preferred energy source
Additional by-products of urea and ammonia
We would rather use protein to repair muscle than as an energy source
Aerobic breakdown of protein
Proteins turns into amino acids and gets deaminated. Then entres the citric acid cycle, then the electron transport system and gets turned into H2O and ATP
Recovery Time
The time to recover from exercise varies
For steady-state aerobic exercises (less than 50-60% of VO2 max for non endurance athletes) or maximum-intensity work for 10-15s (ATP-CP), very little muscle aciditly and lactate accumulates
Recovery is rapid
If body temp is not significantly elevated the EPOC will not be large
Glycogen fuel may be depleted by only significantly in extended endurance like half-marathons and above
Recommened Recovery Times to Replenish Fuel
Restoration of ATP and CP
2-3 mins
EPOC (Rapid Phase)
3-5 mins
EPOC (Slow Phase)
30mins - 1 hour
Removal of lactate from muscle and bloow during exercise-recovery
30min - 1 hour
Removal of lactate from muscles and blood during rest-recovery
1-2 hours
Restoration of muscle glycogen after a long intermittent exercise like a soccer game
5-24 hours
Restoration of muscle glycogen after a prolong exercise like a marathon
10-46 hours
Percentage of Use of the 3 energy systems
Very short and very High intensity will use the ATP-CP systems
Short and High Intensity will use the anaerobic glycolysis system
Medium length and moderate intensity will use aerobic glycolysis system
Long and lighter intensity will use the aerobic lipolysis
Oxygen Consumption during exercise
there is an oxygen deficit during exercise at the start of exercise
that why we warm up so that by game time our bodies won’t be oxygen deprived
when in oxygen deficit we must use our anaerobic system