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How long does the delayed antigenic reaction last for in Type IV Hypersensitivity?
24 to 48 hours
What is the primary cell in Type IV Hypersensitivity?
T lymphocytes
Does T lymphocytes involve antibodies?
No
What is released by T cells that causes CD4+ T cell-mediated inflammation?
Cytokines
What is the function of CD8+ T cells?
Directly kills cells
What is the indicator for tissue rejection?
Separate skin flap
What causes Tuberculin reaction?
PPD
What is the standard test to diagnose Tuberculosis?
Mantoux test
How long does it take for results of a Mantoux test to come out?
48 - 72 hours
What is the skin condition caused by Type IV Hypersensitivity?
Contact dermatitis
What is the buccal mucosa associated with contact with amalgam?
Lichenoid lesion
What are the two main features of cinnamon allergy?
1. Mucosal sloughing/ulceration
2. Tenderness/burning pain
What are the four differential diagnosis of cinnamon allergies?
1. Traumatic ulcer
2. Benign lesions
3. Dysplasia
4. Squamous cell carcinoma
How long does it take for lesions in cinnamon allergies to resolve?
3 weeks