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Phase 1 of wound healing
Inflammation & Debridement (0–3/5 days): hemostasis, vasodilation, WBCs, neutrophils → macrophages, debris removal, growth factor release
Phase 2 of wound healing
Proliferation/Repair (3–5 days): angiogenesis, fibroblasts → collagen, myofibroblasts → contraction, granulation tissue, epithelialization
Phase 3 of wound healing
Maturation/Remodeling (7–14 days+): apoptosis, collagen remodeling, scar forms (70–80% tensile strength)
Clean wound
Surgical, aseptic conditions
Clean-contaminated wound
Minor break in asepsis or entry into GI/GU with minimal contamination; <6 hours old
Contaminated wound
Foreign debris, spillage, major aseptic break; >6 hours old
Dirty wound
Old or infected wound; >12 hours old; >10^5 organisms/gram tissue
Primary closure
Immediate closure; clean or clean-contaminated wounds
Delayed primary closure
2-5 days post-injury before granulation; clean-contaminated or contaminated
Secondary closure
>5 days after injury once granulation tissue forms
Healing by second intention
Wound heals on its own via granulation, epithelialization, contraction
Laceration
Cu/tear in skin; cleaned, lavaged, surgically closed
Abrasion
Superficial dermal injury; heals by re-epithelialization; keep moist
Degloving injury
Skin sheared off; high infection risk; may need grafting
Bite wounds (cats vs dogs)
Cats: small punctures, high infection; Dogs: variable, deeper damage possible
Gunshot wounds
Deep, contaminated, extensive internal damage; often surgical
Penetrating objects (knife, arrow, stick)
DO NOT REMOVE; stabilize and surgically explore
First-degree burn
Epidermis only; pain, redness
Second-degree burn
Epidermis + dermis; blistering, drainage
Third-degree burn
Full thickness kin; eschar, loss of pain, scarring
Fourth-degree burn
Skin, muscle, tendon, bone; critical; surgery required
Decubital ulcer cause
Prolonged pressure → decreased blood flow → tissue death
Pressure sore prevention
Repositioning, nutrition, cleanliness, padded bedding
Common factors delaying healing
Diabetes, steroids, FeLV/FIV, geriatric age, obesity, malnutrition, necrosis, hypotension, hypothermia
Initial wound management
Stabilize patient, cover wound, clip, clean surrounding tissue, lavage
Ideal lavage pressure
7-8 psi
Common lavage fluids
LRS or 0.9% NaCl (warm)
Skin graft
Skin moved without blood supply; needs vascular bed
Skin flap
Skin rotated with blood supply intact; better healing
Skin advancement
Reduces tension via undermining, releasing incisions
Therapeutic laser benefits
Pain relief, less inflammation, greater angiogenesis, faster healing
PRP (Platelet-Rich Plasma)
Autologous platelets release growth factors; antimicrobial benefits
Passive drain
Penrose; gravity/capillary; cannot quantify; infection risk
Active drain
Jackson-Pratt; suction; measurable output
When to remove drain
1-2 mL/kg/day or plateaued normal fluid
Primary layer
Contacts wound; debridement, medication, moisture control
Secondary layer
Absorption, comopression, stabilization
Tertiary layer
Protection, secures bandage
Robert Jones bandage
Thick, bulky; temporary immobilization of distal limb
Modified Robert Jones
Less bulky; toes exposed; splint may be added
Tie-over bandage
Hard-to-bandage areas (axilla, inguinal)
Spica splint
Immobilizes shoulder or hip; limb wrapped to torso
Ehmer sling
Pelvic limb; femoral head luxation
Velpeau sling
Forelimb; shoulder injuries
Strike-through means what?
Bandage must be changed
Signs bandage too tight
swelling, chewing, necrosis risk
E-collar purpose
Prevent bandage destruction
Angiogenesis
Formation of new blood vessels
Apoptosis
Programmed cell death
Debridement
Removal of necrotic tissue
Exudate
Fluid leaked from vessels into tissue