Dopamine Antagonists
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Description and Tags
Anti-emetic
Last updated 8:45 PM on 10/16/25
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4 Terms
1
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Drugs in class
metoclopramide (Reglan)
prochlorperazine (Compazine)
promethazine (Phenergan)
droperidol (Inapsine)
2
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Properties/MOA
-Suppress emesis by blocking
dopamine 2 receptors
• Increases gastric motility
• Prokinetic agent
3
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Effects/Adverse Rxn
• EPS
→ All can cause EPS:
(twitching, muscle
spasms, twisted
posture
4
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Nursing info
-Monitor BP & HR
• Phenothiazines:
→ Compazine, Phenergan
• Butyrophenones:
→ Inapsine
Note 
Flashcards (35)