Ch5: Neurotransmitter systems - Central nervous system

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11 Terms

1
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Where is the Cholinergic - Acetylcholine located?

Nucleus basalis of Meynert

<p><em>Nucleus basalis of Meynert</em></p>
2
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What does Cholinergic - Acetylcholine regulate?

Wakefulness, attention, memory.

<p>Wakefulness, attention, memory.</p>
3
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What does a decrease of Cholinergic - Acetylcholine lead to?

Alzheimer.

<p>Alzheimer. </p>
4
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Where is the Dopaminergic - Dopamine located?

Basal ganglia.

<p><em>Basal ganglia</em>.</p>
5
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What are the 2 pathways of the Dopaminergic - Dopamine system? What do they regulate? What do the insufficiencies and abundancies lead to?

Nigrostratial pathway

  • Motor behavior

    • Decrease leads to Parkinsons.

Mesolimbic pathway

  • Reward and pleasure

    • Increase leads to Schizophrenia.

  • Attention

    • Decrease leads to ADHD.

<p>Nigrostratial pathway</p><ul><li><p>Motor behavior</p><ul><li><p><em>Decrease</em> leads to Parkinsons.</p><p></p></li></ul></li></ul><p>Mesolimbic pathway</p><ul><li><p>Reward and pleasure</p><ul><li><p><em>Increase</em> leads to Schizophrenia.</p></li></ul></li><li><p>Attention</p><ul><li><p><em>Decrease</em> leads to ADHD.</p></li></ul></li></ul><p></p>
6
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Where is the Noradrenergic - Norepinephrine located?

Iocus coeruleus.

<p><em>Iocus coeruleus</em>.</p>
7
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What does the Noradrenergic - Norepinephrine regulate?

Emotional tone (mood).

<p>Emotional tone (mood).</p>
8
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What does an abundancy / insufficiency of Noradrenergic - Norepinephrine lead to?

  • Increase leads to Mania (overexcited behavior)

  • Decrease leads to Depression, ADHD

<ul><li><p><em>Increase</em> leads to Mania (overexcited behavior)</p></li><li><p><em>Decrease</em> leads to Depression, ADHD</p></li></ul><p></p>
9
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Where is the Serotonergic - Serotonin located?

Raphé Nuclei.

<p><em>Raphé Nuclei</em>. </p>
10
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What does Serotonergic - Serotonin regulate?

Wakefulness during movement.

<p>Wakefulness during movement.</p>
11
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What does an abundancy / insufficiency of Serotonergic - Serotonin lead to?

  • Increase leads to Schizophrenia

  • Decrease leads to Depression, OCD, SIDS, sleep apnea

<ul><li><p><em>Increase</em> leads to Schizophrenia</p></li><li><p><em>Decrease</em> leads to Depression, OCD, SIDS, sleep apnea</p></li></ul><p></p>

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