Enzyme-substrate specificity and denaturation

what can alter the structure of enzymes (just like proteins)

ph and temperature

denatured

the shape of the active site is changed considerably

what is compromised as a result of denatruation

enzyme-substrate specificity is compromised so will lose function

high temperature denaturation

extra energy leads to increased vibration, breaking intra-molecular bonds

changes in pH denatruation

higher or lower concentration of hydrogen ions, hence hydrogen bond within the enzyme are broken

what happens when temperature is increased in a reacton

more products are produced per unit of time

how does pH deviation from an enzyme’s optimum affect its structure and activity

pH above or below the optimum alters (reversibly denatures) the enzyme’s structure

what is disrupted when the pH deviates in a reaction

bonding pattern is disrupted changing the 3D shape of the molecule reversibly