Nguyen (2026); HIV Antiretroviral Pharmacology (Brand/Generics/Combo/MOA)

Ziagen

Abacavir (ABC)

Emtriva

Emtricitabine (FTC)

Epivir

Lamivudine (3TC)

Viread

Tenofovir disoproxil fumarate (TDF)

Vemlidy

Tenofovir alafenamide (TAF) *For HepB Only

Retrovir

Zidovudine (AZT)

Sustiva

Efavirenz (EFV)

Edurant

Rilpivirine (RPV)

Pifeltro

Doravirine (DOR)

Viramune / Viramune XR

Nevirapine (NVP)

Isentress / Isentress HD

Raltegravir (RAL)

Tivicay

Dolutegravir (DTG)

Vocabria (PO)

Cabotegravir (CAB) *PO Formulation for Treatment only

Apretude (PrEP)

Cabotegravir (CAB) *Long acting IM injection

Prezista

Darunavir (DRV)

Reyataz

Atazanavir (ATV)

Norvir

Ritonavir (RTV)

Kaletra

Lopinavir/ritonavir (LPV/r)

Tybost

Cobicistat (COBI)

Sunlenca

Lenacapavir (LEN) *For Treatment only

Yeztugo

Lenacapavir (LEN) *For Prevention only

COMBINATION

PRODUCTS

Epzicom

Abacavir + Lamivudine

Truvada

Tenofovir DF + Emtricitabine

Descovy

Tenofovir AF + Emtricitabine

Combivir

Zidovudine + Lamivudine

Trizivir

Zidovudine + Lamivudine + Abacavir

Cimduo

Tenofovir DF + Lamivudine

Atripla

Efavirenz + Tenofovir DF + Emtricitabine (STR)

Symfi / Symfi Lo

Efavirenz + Tenofovir DF + Lamivudine (STR)

Complera

Rilpivirine + Tenofovir DF + Emtricitabine (STR)

Odefsey

Rilpivirine + Tenofovir AF + Emtricitabine (STR)

Delstrigo

Doravirine + Tenofovir DF + Lamivudine

Stribild

Elvitegravir + Cobicistat + Tenofovir DF + Emtricitabine (STR)

Genvoya

Elvitegravir + Cobicistat + Tenofovir AF + Emtricitabine (STR)

Triumeq

Dolutegravir + Abacavir + Lamivudine (STR)

Biktarvy

Bictegravir + Tenofovir AF + Emtricitabine (STR)

Dovato

Dolutegravir + Lamivudine (STR)

Juluca

Dolutegravir + Rilpivirine (STR)

Evotaz

Atazanavir + Cobicistat

Prezcobix

Darunavir + Cobicistat

Symtuza

Darunavir + Cobicistat + Tenofovir AF + Emtricitabine (STR)

Cabenuva

Cabotegravir + Rilpivirine (IM injection)

GENERIC

MECHANISM

Abacavir (ABC)

NRTI — competes with nucleosides, terminates HIV RNA→DNA transcription

Emtricitabine (FTC)

NRTI — competes with nucleosides, terminates HIV RNA→DNA transcription

Lamivudine (3TC)

NRTI — competes with nucleosides, terminates HIV RNA→DNA transcription

Tenofovir DF (TDF)

NtRTI — competes with nucleotides, terminates HIV RNA→DNA transcription

Tenofovir AF (TAF)

NtRTI — competes with nucleotides, terminates HIV RNA→DNA transcription

Zidovudine (AZT)

NRTI — competes with nucleosides, terminates HIV RNA→DNA transcription

Efavirenz (EFV)

NNRTI — non-competitively binds Reverse Transcriptase, inhibits enzyme function

Rilpivirine (RPV)

NNRTI — non-competitively binds Reverse Transcriptase, inhibits enzyme function

Doravirine (DOR)

NNRTI — non-competitively binds Reverse Transcriptase, inhibits enzyme function

Nevirapine (NVP)

NNRTI — non-competitively binds Reverse Transcriptase, inhibits enzyme function

Raltegravir (RAL)

INSTI — inhibits integrase, blocks viral DNA integration into host genome

Dolutegravir (DTG)

INSTI — inhibits integrase, blocks viral DNA integration into host genome

Elvitegravir (EVG)

INSTI — inhibits integrase, blocks viral DNA integration into host genome