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Cardiac Muscle Characteristics
-Involuntary
-Striated
-Uninucleated
-Short, highly branched fibers
Involuntary
automatically done (autonomic nervous system)
Cause of striation
sarcomeres (contractile unit)
Sarcomeres composed of:
Actin and myosin
How are the short, branched fibers of the heart connected?
intercalated discs
Intercalated disc junction types:
-desmosomes
-gap junctions
Desmosomes in intercalated discs function:
creates a physical connection
Gap junctions in intercalated discs function:
allow AP to pass through
What causes the heart to involuntarily beat?
Autorhythmic fibers
Characteristics of autorhythmic fibers
-self excitable (do not need outside stimulus)
-generate AP’s automatically
Autorhythmic fibers function:
-pacemaker
-form the conduction system
Conduction system:
pathway for movement of electrical impulses that stimulate the contraction of the atria and ventricles
1st step in conduction system pathway
the SA node spontaneously depolarizes to threshold and propagates to each atrium simultaneously
SA node is composed of
a collection of autorhythmic fibers
2nd step in conduction system pathway
AP reaches the AV node which delays the AP so that the ventricles can fill with blood
3rd step in conduction system pathway
AP enters the Bundle of His (in the ventricle)
4th step in conduction system pathway
AP enters through the left and right bundle branches
5th step in conduction system pathway
the AP reaches the Purkinje fibers
Purkinje fibers function
conduct the AP from the apex up to the ventricle myocardium for contraction
Factors affecting the conduction pathway
-SA node
-Nervous system slows down AP timing
-Hormones
SA node as an affecting factor:
generates an AP every .6 seconds
Nervous system slows down the conduction pathway through:
the parasympathetic nervous system (Acytacholine)
How do hormones modify the timing of the conduction pathway?
epinephrine releases during certain activities
Cardiomyocyte AP’s
depolarization
plateau
repolarization
Plateau of a cardiomyocyte AP
because Ca2+ channels open up, allowing it into the cell combatting the K+ leaving the cell causing a plateau
Ca2+ significance
needed for contraction
Differences in a cardiomyocyte AP
-takes longer
-RMP -90mV
-Ca2+ needed to contract
-threshold is -75mV
-no undershoot
Which way do AP’s get sent in the heart?
in both directions of the cardiac muscle
How is ATP produced?
through aerobic cellular respiration
Oxygen for aerobic cellular respiration is generated through:
-coronary circulation
-myoglobin
What do cardiac muscle cells possess a lot of?
mitochondria