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substance use disorder
substances produce such an intense activation of the reward system that normal activities may be neglected; pharmacological mechanisms by which each class of drugs reward are different, but the drugs typicaly activate the system and produce feelings of pleasure, often referred to as a “high”
substance use disorder symptoms
impaired control, social impairment, risk use, tolerance/withdrawal symptoms
substance use disorders
alcohol, opioid, stimulants
substance use disorder nursing assessment
reason for seeking tx, detailed hx of pt’s past substance use, previous detoxes, previous periods of sobriety, tox screen, symptoms of withdrawal, medical hx, psychosocial hx, safety, coping style
substance use disorder nursing interventions/tx
SBIRT- screening, brief intervention, referral to treatment
cognitive + CBT
enhancing coping skills
group intervention and early recovery
individual therapies
family therapy
harm reduction strategies
peer support self help groyp
motivational interviewing
substance use
indigestion, smoking, sniffing, or injection of mild altering substance
substance abuse
use for purposes of intoxication or beyond intended use
physiological dependence
body has physical reaction to medication
psychological dependence
when you physically want the medication
withdrawal
symptoms occurring when blood o tissue concentrations of substance decline
detoxification
process of safe withhdrawal
psychotropic
a substance that affects your mental state and ability to cognitively function
psychoactive
substance that passess the BBB
neurotransmitters in the reward pathway of the brain
dopamine, glutamate, GABA, serotonin; connected to the areas of the brain that control behavior and memory
makes connections between the activity and the pleasure, ensuring that we will repeat the behavior
key diagnostics for substance use disorders
impaired glucose control
social impairment
risky use of substance and failure to abstain despite difficulty
pharmacologic effects: tolerance/withdrawal syndrome
withdrawal syndrome
occurs when blood of tissue concentration of a substance declines
trends in substance use in the US
alc most common, marijuana follows
social risk factors for substance use
environmental factors, peer influences, dysfunctional family dynamics, deviance or social madalaptation, consequences of action
Psychological risk factors for substance use
depressed mood, low self esteem, self derogatory, excessive dependency, increased need for success or power, inability to cope with overwhelming feelings, personality disorder or hyperactivity
reasons pts don’t seek treatment
thinking they can handle their own alc or drugs use on their own
not being able to start treatment
not being ready to stop or cut back on using alc or drugs
being worried about what others will think or say
expensive
not enough time
lack of knowledge on where or how to get treatment
being worried information won’t be kept private
thinking bad things will happen: losing job, home, or children
harm reduction examples
nicotine patch/gum, opioid substitution: methadone/buprenorphine, needle exchange programs for IV heroin users, narcan kits to first responders, decriminalization
Motivational interviewing
a guiding style of communication that sits between following (good listening) and directing (giving information and advice)
Designed to empower people to change by drawing out their own meaning, importance and capacity for change
based on a respectful and curious way of being with people that facilitates that natural process of change and honors client autonomy
alc effects
sedation, decreased inhibitions, relaxation, decreased coordination, slurred speech, nausea
alc overdose
resp depression, cardiac arrest
alc withdrawal
tremors; elevated temp, pulse, BP, diaphoresis; anxiety; delirium tremens (autonomic hyperarousal, disorientation, hallucinations); grand mal seizures, status epilepticus; DEATH
aka (acloholic ketoacidosis)
a life threatening metabolic disturbances caused by heavy alc use, starvation, and vomiting; leads to accumualtion of acidic ketones and metabolic acidosis
aka (alcoholic ketoacidosis) symptoms
abd pain, nausea, vomiting, confusion and rapid, labored breathing
alc prolonged use
affects all symptoms of the body
alcohol-induced amnestic disorders
wernicke encephalopathy
Korsakoff’s amnestic syndrome
Wernicke encephalopathy
degenerative brain disorder caused by thiamine deficiency characterized by vision impairment, ataxia, hypotension, confusion, and coma
Korsakoff amnestic syndrome (chronic)
problem acquiring new information and retrieving memories
Korsakoff amnestic syndrome (chronic) symptoms
amnesia, confabulation (e.g. telling a plausible but imagined scenario to compensate for memory loss), attention deficit, disorientation, vision impairment
CAGE- for alcohol withdrawal
cut, annoyed, guilty, eye
nursing assessments for alcohol withdrawal
CIWA-Ar; prevent and manage seizures is a priority
electrolyte abnormalities for alc withdrawal
hypomagnesemia, hypokalemia, hypophosphatemia, hyponatremia
CIWA screening
Max score=67Â
Client receives medication based on scoreÂ
Client scoring less than 10 generally do not require medicationÂ
Sections= nausea/vomiting, tremors, paroxysmal sweats, anxiety, agitation, tactile disturbances, auditory disturbances, visual disturbances, HA/fullness in head, orientation
CIWA <10 score
very mild withdrawal
CIWA 10-15 score
mild withdrawal
CIWA 16-20 score
moderate withdrawal
CIWA >20 score
severe withdrawal
medications for moderate and severe withdrawal
Benzodiazepines
Barbiturates
Propofol
Benzodiazepines for withdrawal
diazepam (Valium), Lorazepam (Ativan), chlordiazepoxide (Librium)
Barbiturates
phenobarbital (Sezaby)
opioid effects
euphoria, sedation, reduced libido, memory and concentration difficulties, analgesia, constipation, constricted pupils
opioid overdose
resp depression, stupor, coma, DEATH
opioid withdrawal
GI upset, abd cramps, rhinorrhea, watery eyes, dilated pupils, yawning, “goose flesh”, diaphoresis, nausea, diarrhea, anorexia, insomnia, feverÂ
opioid prolonged use
can lead to criminal behavior to get money for drugs, risk for infection-related to needle use (e.g. HIV, endocarditis, hepatitis)
nursing assessment for opioid use
COWS
COWS- clinical opioid withdrawal scale
resting pulse rate, GI upset, sweating, tremor, restlessness, yawning, pupil size, anxiety/irritability, bone or joint aches, gooseflesh skin, runny nose or tearing
OUD meds
methadone, buprenorphine, naltrexone, naloxone
cannabis effects
euphoria or dysphoria, relaxation and drowsiness, heightened perception of color and sound, poor physical coordination, spatial perception and time distortion, unusual body sensations (e.g. weightlessness, tingling), dry mouth, dysarthria, and cravings for particular foods
cannabis overdose
increased HR, reddened eyes, dysphoria, lability, disorientation
cannabis prolonged use
can decrease motivation and cause cognitive deficits (e.g. inability to concentrate, impaired memory)
stimulant effects
euphoria, initial CNS, stimulation and then depression, wakefulness, decreased appetite, insomnia, paranoia, aggressiveness, dilated pupils, tremors
stimulants overdose
cardiac arrhythmias or arrest, increased or lowered BP, resp depression, chest pain, vomiting, seizures, psychosis, confusion, seizures, dyskinesias, dystonias, coma
stimulants withdrawal
depression; psychomotor retardation at first and then agitation; fatigue and then insomnia; severe dysphoria and anxiety; cravings, vivid, unpleasant dreams; increased appetite; amphetamine withdrawal is not as pronounced as cocaine withdrawal
stimulants prolonged use
weight loss resulting malnutrition and increased suspectibility to infectious diseases
schizophrenia like syndrome: paranoid ideation, thought disturbance, hallucinations, and stereotyped movements
hallucinogens effects
euphoria or dysphoria, altered body image, distorted or sharpened visual and auditory perceptions, depersonalization, bizzare behavior, confusion, incoordination, impaired judgement and memory, signs of sympathetic and parasympathetic stimulation, palpitations (blurred vision, dilated pupils, sweating)
hallucinognens overdose
paranoid, ideas of reference, fear of losing one’s mind, depersonalization, derealization, illusions, hallucinations, synesthesia, self destructive or aggressive behavior, tremors
hallucinogens withdrawal
flashbacks, mood symptoms
opioids commonly used
oxycodone, hydrocodone, morphine, fentanyl, codeine, barbituates (e.g. pentobarbital), and benzodiazepines
amphetamines commonly used
adderall, dexedrine, and methylphenidate (concerta, ritalin)
OTC drugs commonly used
cough medicine containing dextromethorphan (DXM)
physical intoxication of alc
slurred/incoherent speech, nausea/vomiting, drowsiness, dizziness, reduced alertness, loss of coordination, instability, flushed face, red/watery eyes, sweating
physical intoxication of opioids
altered mental status (confusion, delirium, or decreased awareness or responsiveness)
physical intoxication of stimulants
amphetamines (dilated pupils, twitching, HTN, tachycardia); Cocaine (dilated pupils, HTN, runny nose or nosebleeds, anorexia)