antifungal agents
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5 Terms
1
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polygenes
bind to ergesterol, for pores in the membrane → leakage
toxic to human
2
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Azoles
target ergestroil synthesis, block production, impares fluidity, increases toxic intermediate buildup.
3
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allyamines
inhibit monooxy precursor, produce toxic sterol buildup - in skin and nails
4
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echinocandins
bidn to b13-glucans, prevent crosslinking - osmatic lysis
5
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5-F4
pro-enzyme, targets thymidylate synthase, cases RNA misscoding
Note 
Flashcards (73)