week 8 UTI Meds

medications used to treat Urinary Tract Infections (UTI)

Sulfa Antibiotic: prototype - (Trimethoprim-sulfamethoxazole (Bactrim))

Alpha Agonist, Urinary Analgesic: prototype - Phenazopyridine Hydrochloride (Pyridium, AZO))

Sulfa Antibiotic: prototype - (Trimethoprim-sulfamethoxazole (Bactrim)) Indications

Uncomplicated cystitis

Sulfa Antibiotic: prototype - (Trimethoprim-sulfamethoxazole (Bactrim)) MOA

Combination medication that work together to inhibit folic acid synthesis (in 2 different ways)

Sulfa Antibiotic: prototype - (Trimethoprim-sulfamethoxazole (Bactrim)) considerations

Sulfa allergies

Sulfa Antibiotic: prototype - (Trimethoprim-sulfamethoxazole (Bactrim)) patient teaching/education

• take all medications

• force fluids (must drink a lot of fluids due to crystals forming)

• Hygiene

Sulfa Antibiotic: prototype - (Trimethoprim-sulfamethoxazole (Bactrim)) Administration considerations

dosed two times per day

Sulfa Antibiotic: prototype - (Trimethoprim-sulfamethoxazole (Bactrim)) Therapeutic effects

Kills bacteria

Sulfa Antibiotic: prototype - (Trimethoprim-sulfamethoxazole (Bactrim)) Adverse/side effects

Allergies

Alpha Agonist, Urinary Analgesic: prototype - Phenazopyridine Hydrochloride (Pyridium, AZO)) Indications

Urinary burning, frequency, pain and urgency

Alpha Agonist, Urinary Analgesic: prototype - Phenazopyridine Hydrochloride (Pyridium, AZO)) MOA

Local anesthetic effect on GU mucosa

Alpha Agonist, Urinary Analgesic: prototype - Phenazopyridine Hydrochloride (Pyridium, AZO)) Considerations

• allergies

• pregnancy

• renal excretion

Alpha Agonist, Urinary Analgesic: prototype - Phenazopyridine Hydrochloride (Pyridium, AZO)) Patient teaching/education

• only take for 2 days

• take with meals and 8oz water

• turns urine orange and tears

• can alter results of urine C&S

Alpha Agonist, Urinary Analgesic: prototype - Phenazopyridine Hydrochloride (Pyridium, AZO)) Administration considerations

• give for 2 days max

• I&O

Alpha Agonist, Urinary Analgesic: prototype - Phenazopyridine Hydrochloride (Pyridium, AZO)) Therapeutic effect

decreased symptoms of UTI

Alpha Agonist, Urinary Analgesic: prototype - Phenazopyridine Hydrochloride (Pyridium, AZO)) adverse/side effects

• headache

• indigestion, N/V

• urine and secretion discoloration

• kidney excretion