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agonist
the primary muscle responsible for producing a particular movement at a joint
antagonist
a muscle that opposes the action of the agonist, helping control or refine the movement
synergist
a muscle that assists the agonist in performing its actin
fixator
a muscle that stabilizes a joint or bone so taht the agonist can function effectively
origin
the fixed attachment point of a muscle, typically on the proximal or less mobile bone
insertion
the moveable attachment point of a muscle, usually on the distal or more mobile bone
lever system
a mechanical model describing how bones and muscles interact to create movement, with classes based on force, load, and fulcrum position
sarcomere
the functional unit of contraction in a muscle fiber, made up of overlapping thick and thin filaments
myofibril
bundles of protein filaments (myofilaments) inside muscle fibers, responsible for contraction
myosin
a motor protein that forms thick filaments; it binds to actin and pulls during contraction
actin
a structural protein forming thin filaments; it contains binding sites for myosin
troponin
a regulatory protein on thin filaments that binds calcium and initiates the movement of tropomyosin to expose actin’s binding sites
tropomyosin
a regulatory protein that blocks actin’s binding sites in relaxed muscle; it shifts when troponin binds calcium
sarcoplasmic reticulum (sr)
specialized smooth endoplasmic reticulum in muscle cells that stores and releases calcium ions, triggering contraction
t-tubules
invaginations of the sarcolemma that help spread the action potential deep into the muscle fiber
muscle tension
the force generated by muscle fibers during contraction, important in both movement and clinical assessment of functione
excitability
the ability of muscle cells to respond to a stimulus, typically from a neuron; essential for communication between nervous and muscular systems
neuron
a specialized cell that sends and receives electrical signals in the nervous system
neuroglia
supporting cells that protect, nourish, and insulate neurons; aka glial cells
central nervous system
the brain and spinal cord; processes information and makes decisions
peripheral nervous system
all the nerves outside the cns; connects the brain and spinal cord to the rest of the body
resting membrane potential
the electrical charge difference across a neuron’s membrane when it is not sending a signal
action potential
a fast electrical signal that travels along a neuron’s axon to communicate with other cells
voltage-gated ion channel
a protein in the neuron’s membrane that opens or closes in response to changes in voltage
synapse
the connection between two neurons (or a neuron and another cell) where signals are passed
neurotransmitter
a chemical messenger that carries a signal across a synapse to the next cell
myelin
a fatty covering around some axons that speeds up the movement of electrical signals