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Sensory Receptors
Specialized cells or structures that detect changes in the environment (stimuli) and send signals (impulses) to the brain.
Sensation
The awareness of a stimulus once it reaches the brain.
Perception
The brain's interpretation of sensory information; the subjective experience.
Stimulation
A stimulus activates a sensory receptor.
Transduction
Receptors convert the stimulus into an electrical signal.
Impulse Transmission
Sensory neurons carry the signal to the CNS.
Perception (in sensory detection)
The cerebral cortex processes and interprets the signal.
Analog Signals
Stimuli are analog (continuous), but sensory impulses are transformed into digital signals (action potentials = 0s and 1s).
Frequency of Action Potentials
Stronger stimuli = higher frequency of action potentials.
Sensory Adaptation
The ability to ignore unimportant stimuli over time.
Nociceptors
Pain receptors that do not adapt.
General Receptors
Widely distributed receptors found in skin and joints.
Special Receptors
Receptors found in specific organs such as eyes, ears, and nose.
Mechanoreceptors
Receptors that detect touch, pressure, and vibration.
Thermoreceptors
Receptors that detect temperature changes.
Nociceptors (function)
Receptors that detect pain and tissue damage.
Chemoreceptors
Receptors that detect chemicals (taste, smell).
Photoreceptors
Receptors that detect light (eyes only).
Exteroceptive Senses
Detects touch, pressure, temperature, pain (skin).
Interoceptive Senses
Detects viscera/internal organs.
Proprioceptive Senses
Detects muscle and joint position (body awareness).
Referred Pain
Brain misinterprets source due to shared nerve pathways (e.g., heart attack pain felt in arm).
Acute Pain
Fast, sharp pain transmitted by myelinated A-delta fibers.
Chronic Pain
Slow, dull pain transmitted by unmyelinated C fibers.
Thalamus (pain)
Brain area responsible for awareness of pain.
Cerebral Cortex (pain)
Brain area that locates pain and processes emotional response.
Natural Analgesics
Substances like endorphins, enkephalins, and serotonin that control pain.
Taste Buds
Contain ~50-100 taste cells per bud, located on papillae of the tongue.
Taste Receptors
Respond to sweet, sour, salty, bitter, umami, and also to spicy (pain) and cool (menthol) via nociceptors.
Outer Ear
Auricle + Auditory Canal
Middle Ear
Tympanic membrane + Ossicles (MIS)
Inner Ear
Cochlea (hearing), Vestibule & Semicircular canals (equilibrium)
Hearing Process
1. Sound waves → Tympanic membrane vibrates. 2. Ossicles (Malleus-Incus-Stapes) amplify signal. 3. Stapes → Oval Window → Cochlear fluid waves. 4. Basilar membrane vibrates → Hair cells bend. 5. Hair cells depolarize → Impulses via CN VIII to brain.
Static equilibrium
Head position (Vestibule).
Dynamic equilibrium
Head movement (Semicircular canals).
Congenital Insensitivity to Pain
Genetic disorder; no pain sensation.
Phantom Limb Pain
Brain perceives pain from a missing limb.
Anosmia
Loss of sense of smell.
Tinnitus
Ringing in ears; often linked to cochlear damage.
Sensation
The awareness of a sensory impulse.
Perception
The brain's interpretation of a sensory impulse.
Thermoreceptors
Types of sensory receptors that detect temperature changes.
Graded receptor potential
Generated when a receptor is stimulated, which may lead to an action potential.
Sensory adaptation
A decrease in response to a continuous stimulus, allowing the brain to ignore unimportant information.
Nociceptors
Pain receptors that do not adapt to continuous stimuli.
TrpV1
A type of nociceptor and thermoreceptor that responds to extreme temperatures and capsaicin.
Referred pain
Pain perceived at a location other than the site of the painful stimulus, due to shared nerve pathways.
A-delta fibers
Type of pain fibers associated with acute pain.
C fibers
Type of pain fibers associated with chronic pain.
Taste sensations
The five basic taste sensations: sweet, salty, sour, bitter, and umami.
Cranial nerves for taste
Facial (VII), Glossopharyngeal (IX), and Vagus (X).
Olfactory receptors
Located in the upper nasal cavity, on the olfactory epithelium.
Chemoreceptors
Type of receptors involved in smell.
Cochlea
Contains the organ of Corti and is responsible for hearing.
Semicircular canals
Detect rotational movement and help with dynamic equilibrium.
Organ of Corti
Structure that contains hair cells that generate impulses for sound.
Sound transduction
Sound waves vibrate the tympanic membrane, move ossicles, push fluid in cochlea, which moves hair cells that send nerve impulses.
Proprioceptors
Detect body position, muscle length, and tension.
Muscle spindles
One of the two main types of proprioceptors.
Golgi tendon organs
One of the two main types of proprioceptors.
Congenital insensitivity to pain
Condition characterized by a complete inability to feel pain.
Thalamus in pain processing
Makes the person aware of pain.
Neurotransmitters that inhibit pain
Endorphins, enkephalins, and serotonin.