Steps of the exogenous pathway

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6 Terms

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Dietary lipids

Released by the liver

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Intestinal cell

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chylomicron

Synthesized by the intestine to transport dietary fat and fat-soluble vitamins

Picks up A, C, and E in plasma

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capillaries (lacteals)

Has lipoprotein lipase (LPL)

Synthesized in muscle, heart, and adipose tissue

Hydrolyzes TGs carried in chylomicrons and VLDL to fatty acids, which are taken up by cells

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Chylomicron remnant

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Liver

LDL receptor is important here, as it recognizes Apo B-100 and Apo E, which allows the liver to uptake LDL, chylomicron remnants and IDL, which happens via endocytosis. LDL is degraded by lysosomes to release cholesterol

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