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Dietary lipids
Released by the liver
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Intestinal cell
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chylomicron
Synthesized by the intestine to transport dietary fat and fat-soluble vitamins
Picks up A, C, and E in plasma
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capillaries (lacteals)
Has lipoprotein lipase (LPL)
Synthesized in muscle, heart, and adipose tissue
Hydrolyzes TGs carried in chylomicrons and VLDL to fatty acids, which are taken up by cells
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Chylomicron remnant
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Liver
LDL receptor is important here, as it recognizes Apo B-100 and Apo E, which allows the liver to uptake LDL, chylomicron remnants and IDL, which happens via endocytosis. LDL is degraded by lysosomes to release cholesterol
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