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Substance Abuse Disorder
continued use despite disruption or danger; interferes with life responsibilities.
Diminished control
unable to regulate use; cravings/overuse.
Diminished social functioning
drug interferes with school, work, or relationships.
Hazardous use
using despite physical or psychological risks.
Drug action
experience tolerance and withdrawal.
Tolerance
need increasing amounts of a drug to achieve the same effect.
Withdrawal
physical or emotional distress after stopping drug use.
Physical dependence
body requires the drug for normal function.
Psychological dependence
brain craves the drug to feel good or normal.
Blood-brain barrier
protective barrier around the brain; some drugs can cross and affect brain function.
Synergistic effect
combined drugs produce effects stronger than their sum; increases overdose risk.
Alcohol
slows CNS activity; impairs judgment and memory.
Barbiturates
CNS depressants; reduce anxiety and promote sleep; risk of overdose when combined with alcohol.
Opioids
pain relief and euphoria; highly addictive (e.g., morphine, heroin). Can cause drowsiness, nausea, respiratory depression.
Anxiolytics
reduce anxiety without strong sedation; habit-forming with long-term use (e.g., Valium, Xanax, ketamine).
Caffeine
increases alertness and wakefulness; can cause irritability or insomnia in high doses.
Nicotine
highly addictive; stimulates acetylcholine, boosts alertness; found in tobacco.
Cocaine
blocks dopamine reuptake; intense euphoria followed by crash; highly addictive.
Amphetamines
stimulate neural activity, energy, and mood; reduce baseline dopamine; can cause motor issues at high doses.
Methamphetamine
extreme stimulant; dopamine agonist, highly addictive; increases energy, alertness, libido; risks: heart palpitations, skin problems, diarrhea.
Ecstasy (MDMA)
stimulant + mild hallucinogen; increases serotonin → euphoria and social connectedness; risks: dehydration, cognitive impairment, possible heart problems. (grind teeth and slowsw down the world, lights) long term
Near-death experience
altered state of consciousness, similar to psychedelic trip; can affect perception of reality.
Peyote
hallucinogenic cactus used in Native American rituals; can induce visions and spiritual experiences.
Psilocybin mushrooms (shrooms)
hallucinogenic fungi; distort perception, time, and colors; can produce spiritual or mystical experiences.
LSD
powerful hallucinogen; vivid images, altered self-identity, sensory synesthesia; even small doses are potent; risk of 'bad trips.' (bug under skin, very real hallucinogens)
Marijuana (THC)
mild hallucinogen; relaxes, amplifies senses, distorts time; impairs memory and cognitive function; may trigger schizophrenia in predisposed users. (compared pilots normal and marijuana pilots, marijuana pilots failed more/ think you are better than you are)
Agonistic drug
mimics neurotransmitters and activates receptors (e.g., opioids).
Antagonistic drug
blocks neurotransmitter activity or reuptake.
Depressants
class of drugs that slow CNS activity and neural processing; include alcohol, barbiturates, opioids, anxiolytics.
Psychoactive Drug
Chemical substance that change the brain function resulting in alter actions in perceptions
Hallucinogens
Drugs that distorts perceptions that creats csensory, experience without real inputs, ex: (peyote, spear quests, bears or deers be spirit guides)