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What’s the main function of the integumentary system?
protection
Whats the superficial layer of the skin?
epidermis
The epidermis is___
avascular
What cells are the most abundant in the epidermis?
Keratinocytes
What protein do keratinocytes make? what is their product’s function?
They make keratin which makes the epidermis a tough protective layer
What other cells are in the epidermis?
Melanocytes, Langerhan cells, Merkel cells
What do melanocytes make? What is the function of their product?
They make melanin which is pigment, it protects the skin from UV damage
What are Langerhan cells? What is their function?
They are epidermis dentritic cells that alert and activate immune cells to a threat (bacterial/viral invasion)
What are merkel cells? What do they do?
They are sensory nerve endings that serve as touch receptors
What are the 5 layers of the epidermis? (from bottom to top)
Stratum basale, spinosum, granulosum, lucidum, corneum
What’s the acronym for the 5 layers?
Beautiful Skin Glows Like Crystals
What layer is the stratam basale/stratum germinativum? What does it do?
1st layer where stem cells grow into keratinocytes, melanocytes, and langerhan cells it is closest to the dermis
Where are nutrients most abundant in the 5 layers? (Top or Bottom)
Bottom
Which layer is the stratum spinosum? What does it do and what’s in it?
2nd layer (thickest)— many rows of dividing keratinocytes, melanin granules and langerhan’s cells are most abundant here
Which layer is the stratum granulosum? What happens here?
3rd layer— keratinocytes stop dividing, keratin and lamellar granules accumulate: Keratinization- cells harden and fill with keratin. Lamellar granules: contain water-resistant glycolipid
Which layer is the stratum lucidum? What happens here?
4th layer- only in thick skin— “clear layer” it is the flattened, dead, densley packed cells that don’t have organelles
Which layer is the stratum corneum? What happens here?
5th layer: 20-30 cells thick, dead cells completely filled with keratin for protection— layer is replaced by the division of deeper stratum basale cells— regenerates every 25-45 days
What does the dermis do/What is it?
Stretchy envelope that binds the skin— has areolar and dense irregular connective tissue that make up the papillary and reticular areas— thickness varies depending on where it is
What is the papillary layer a part of? What is it and what does it do?
Dermis; superficial dermal region— has capillary loops to bring nutirents to the epidermis, has nerve endings (meissner corpuscles) which are pain and touch receptions. Makes up the patterns of the finger prints and sweat pores
What is the reticular layer a part of? What does it do & whats in it?
Dermis; deepest skin layer, dense irregular connective tissue, blood vessels, sweat and oil glands, deep pressure receptors (lamellar corpuscles) phagocytes
What do collagen fibers do?
Effect toughness of skin— attract and bind to water
What do elastic fibers do/ pertain to?
Elasticity; aging decreases the amount of collagen and elastic fibers decrease, subcutaneous tissue looses fat
What isn’t a layer of the skin?
Hypodermis
What layer does temperature regulation pertain to? What happens?
Dermis(supplies with blood); Warm- capillaries swell with warm blood and skin becomes reddened and warm —— Cold- blood passes the dermis capillaries so internal body temp can stay high
What is the hypodermis? What’s in it and what does it do?
subcutaneous layer, made up mostly of adipose tissue but also has areolar tissue, anchors skin to underlying tissues; shock absorber and insulator
epithelial membranes include the:
cutaneous, mucous, and the serous membranes
the mucous membrane is made of loose (areolar) connective tissue, called:
lamina propia
the lamina propia/mucous membranes line the:
hollow organs and body cavities that open to the exterior
most tissues of the mucosae in the mouth and esophagas are made of:
squamous epithelium
most tissues of the mucosae in the digestive tract are made of:
simple columnar epithelium
Why are mucous membranes called moist membranes?
They are always bathed in secretions and adapted for secretion and absorption and make lubricating mucus
What is the serous membrane made of?
Simple squamous epithelium on areolar connective tissue
Serous membranes— visceral layers line the:
ventral cavity (outer covering of the organs)
Serous layers are separated by ____, which are important to______
Serous fluid ; mobile organs
In the abdominal cavity the serousa lining is called _______.
peritoneum
For the lungs the serosa lining is called ______.
pleurae
Around the heart the serosa lining is called the ______.
pericardia
Synovial membranes are _____.
connective tissues that have no epithelial cells
What do the synovial membranes line?
fibrous capsules that surround joints and make lubricating fluid
The capillary and sweat glands are controlled by the:
nervous system
What is it called when the corneum cells are completely filled with keratin and dead?
They are cornified
What happens when melanin is concentrated in one spot?
It forms freckles or moles
What happens if the body takes in too many UV rays?
Turns leathery, depresses the immune system & skin cancer
What is formed when cell death happens because of an irregular blood supply?
ulcers
How are decubitus ulcers formed?
when bed ridden patients aren’t turned so the pressure is centralized and restricts blood flow which leads to dying of cells and degeneration and ulceration
What pigments contribute to skin color?
Melanin, Carotene, and Hemoglobin
What happens when hemogloben is severely deoxygenized?
cyanosis
Other than pigment, what can affect the appearance of skin?
Emotions
What emotion or bodily issue can redness/ erythema pertain to?
Embarrassment; fever, hypertension, inflammation, or allergy
What emotion or bodily issue can pallor/ blanching pertain to?
stess (fear/anger); anemia, low blood pressure, or impaired blood flow
What bodily issue can a yellow cast pertain to?
Jaundice, liver disorder which is the accumulation of bile pigments in the blood
What bodily issue can a black/blue marks pertain to?
Bruises— blood escaping circulation and clotting in tissue spaces
What does an unusual tendency to bruise mean?
Vitamin C deficiency
What do skin appendages include?
cutaneous glands, hair, hair follicles, and nails
What are cutaneous glands? What do they do?
Exocrine glands; secrete subtances to the surface of the skin through ducts
What two types of cutaneous glands are there?
Sebaceous glands and sweat glands which lay in the dermis
What is the purpose of sebum?
Keeping the skin moisturized & killing bacteria
What happens when sebaceous glands are blocked?
Acne forms
What forms when acne is oxidized and dries?
Blackheads
What forms when acne doesn’t dry or darken?
Whiteheads
What is seborrhea known as?
Cradle cap; over production in sebaceous glands
What else are sweat glands known as?
Sudoriferous glands
what two kinds of sweat glands are there?
eccrine and apocrine
Where are eccrine glands normally? What do they do?
All over the body; secrete sweat consisted of water and salts— mtabolic waste— can promote some bacteria growth
What’s special about eccrine glands?
They have nerve endings which pertain to thermoregulation
Where are apocrine glands normally?
Axillary and genital areas
How to apocrine glads differ to eccrine glands?
They are bigger, empty onto hair follicles, substances also are made of fatty acids and proteins— odorless unless there is bacteria
How are apocrine glands triggered?
Through pain, stress, sexual arousal, puberty through androgens
What is the matrix in terms for nails and hair?
Growth zone
What is the innermost part of the hair called?
medulla
Whats the 2nd layer of the hair called?
cortex
What is the outermost layer of the hair called? What does it have the most of?
cuticle; keratin
Where does the pigment in hair come from?
Melanocytes in the hairbulb
What is the part of the hair that’s outside of the skin called?
The shaft
What determines hair type?
shape of the shaft
What shape is the shaft if hair is curly?
flat and ribbonlike
What shape is the shaft if the hair is straight?
perfectly round and coarse
What shape is the shaft if the hair is wavy?
oval
What is the inner epithelial root a part of?
Hair follicles
What does the inner epithelial root form?
hair
What does the outer fibrous sheath do? What is it?
Supplies blood vessels to the edpidermal portion; dermal connective tissue
What is the papilla a part of?
fibrous sheath
What does the papilla do?
supplies blood to the hair bulb
What does the arrector pili do?
It raises the hair and forms goosebumps when muscles contract
What is the skin that the nail is imbedded into called?
The cuticle
What grows under the nail bed? What is the thick part?
the stratam basale; nail matrix
What is the white crescent part in the nail called?
Lunule
How do the nails appear when blood is rich? What about without?
Pink;Bluish
How many kinds of burns are there?
4
What traits do 1st degree burns have?
only superficial epidermis damage— red and swollen— slight discomfort/bit of pain
What traits do 2nd degree burns have?
injury to the epidermis and superficial part of the dermis— red swollen and blistered but can regrow, painful
What traits do 3rd degree burns have?
epidermis and dermis are destroyed— can extend into subcutaneous tissue, blistering, nerve endings are destroyed so not painful
What traits do 4th degree burns have?
extend beyond subcutaneous tissues to muscle, bones, muscles, or tendons
What’re 2 life threatening problems derivred from burns?
Loss of fluids & Infection
What is the rule of nines?
Division of the body (11 areas in total) where its parts are 9% (groin is 1%) to determine how much fluid must be replased for burn victims
What conditions make burns considered critical?
over 30% of the body has 2nd degree burns/over 10% of the body has 3rd/4th degree burns/3rd/4th degree burns on the face, hands, feet, or genitals/ burns reach airways/circumferential(around the body or limb) burns have occurred
What happens if joints are burnt?
It affects joint mobility
Depending on location what can circumferential burns restrict?
Movement & Breathing
What traits does basal cell carcinoma have?
most common, least dangerous— stratum basale can’t make keratin— slow spreading— shiny dome shaped tumor