lec 10 - Inducing pluripotent stem cells (intro)

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12 Terms

1
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what is reprogramming?

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when does a cell reached the “fixed” state and how?

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is the fixed state flexible/reversible?

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what is dedifferentiation? how does this work?

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what is transdifferentiation?

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what is developmental plasticity

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why are stem cell nuclei said to be more “plastic” than differentiated cells?

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describe the two different types of cell-cell fusion?

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compare and contrast synkarons and heterokaryons

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how does gene expression change in heterotypic fusions?

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can heterotypic fusion be done on all three germ layer cells?

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what are the 4 transcription factors needed for reprogramming to pluripotent cells

  • pluripotent reprogramming by transcription factors was first achieved using these 4 proteins.