lec 10 - Inducing pluripotent stem cells (intro)
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12 Terms
what is reprogramming?
when does a cell reached the “fixed” state and how?
is the fixed state flexible/reversible?
what is dedifferentiation? how does this work?
what is transdifferentiation?
what is developmental plasticity
why are stem cell nuclei said to be more “plastic” than differentiated cells?
describe the two different types of cell-cell fusion?
compare and contrast synkarons and heterokaryons
how does gene expression change in heterotypic fusions?
can heterotypic fusion be done on all three germ layer cells?
what are the 4 transcription factors needed for reprogramming to pluripotent cells
pluripotent reprogramming by transcription factors was first achieved using these 4 proteins.
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