Manor Drills - Module 2

German pharmacist who obtained an impure alkaloid from Atropa belladonna fam. Solanaceae

a.P. Robiquet

b.F. Serturner

c.F. Fluckinger

d.R. Brandes

e.J. Caventou

D

Order the following steps chronologically:

I. Selection

II. Harvesting

III. Garbling

IV. Drying

V. Curing

a.I-II-III-IV-V

b.I-II-IV-V-III

c.II-I-III-IV-V

d.II-I-III-V-IV

e.I-II-III-V-IV

B

Known as the deliberate addition of spurious material to a genuine portion with the intent to defraud

a.Admixture

b.Sophistication

c.Substitution

d.Deterioration

B

Amylose is the linear constituent of starch that is usually 500-800 units long, and produces a deep blue coloration when subjected to Iodine Test. Amylopectin is the branched constituent of starch usually >1000 units long, and produces a blue-violet coloration when subjected to the Iodine Test.

a.Only the first statement is true.

b.Only the second statement is true.

c.Both statements are true.

d.Both statements are false.

B

LEAST SOLUBLE GUM

Sterculia/Karaya Gum; fetid odor, discontinues mucilage

a.Ceratonia siliqua

b.Sterculia urens

c.Anogeissus latifolia

d.Macrocystis pyrifera

e.Furcellaria fastigiata

B

Acacia substitute that forms a more viscous dispersion in cold water than acacia

Indian/Ghatti gum

a.Ceratonia siliqua

b.Sterculia urens

c.Anogeissus latifolia

d.Macrocystis pyrifera

e.Furcellaria fastigiata

C

Thickener and stabilizer used as a chocolate substitute

Caroba/Locust Bean Gum/St. John's Bread

a.Ceratonia siliqua

b.Sterculia urens

c.Anogeissus latifolia

d.Macrocystis pyrifera

e.Furcellaria fastigiata

A

Find the classification of Dioscorea floribunda(Mexican Yam-Constituent: Diosgenin)

I. Cardiac

II. Anthraquinone

III. Saponin

IV. Cyanophore

V. Isothiocyanate

VI. Alcohol

VII. Aldehyde

VIII. Lactone

IX. Flavonol

X. Phenol

a.III

b.IV

c.X

d.IX

e.VII

A

Find the classification of Ammi majus(Bishop flower- Psoralens/Methoxsalen)

I. Cardiac

II. Anthraquinone

III. Saponin

IV. Cyanophore

V. Isothiocyanate

VI. Alcohol

VII. Aldehyde

VIII. Lactone

IX. Flavonol

X. Phenol

a.III

b.IV

c.X

d.IX

e.VIII

E

Find the classification of Urginea maritima(Meditterinian/ White squill- constituen:Scillarenin)- Bufadienolide-Cardia

I. Cardiac

II. Anthraquinone

III. Saponin

IV. Cyanophore

V. Isothiocyanate

VI. Alcohol

VII. Aldehyde

VIII. Lactone

IX. Flavonol

X. Phenol

a.III

b.IV

c.X

d.I

e.VII

D

Find the classification of Aloe barbadinensis (Uracao Aloe- Barbaloin aloe emodin)

I. Cardiac

II. Anthraquinone

III. Saponin

IV. Cyanophore

V. Isothiocyanate

VI. Alcohol

VII. Aldehyde

VIII. Lactone

IX. Flavonol

X. Phenol

a.III

b.IV

c.II

d.IX

e.VII

C

Find the classification of Silybum marianum(Milk Thistle-constituent(Silymarin))

I. Cardiac

II. Anthraquinone

III. Saponin

IV. Cyanophore

V. Isothiocyanate

VI. Alcohol

VII. Aldehyde

VIII. Lactone

IX. Flavonol

X. Phenol

a.III

b.IV

c.II

d.IX

e.VII

D

Nutgall is obtained from the hardened excrescence from the young twigs of Quercus infectoria. Holes are bored in the twigs by the hymenopterous insect Cynips tinctoria.

a.Only the first statement is true

b.Only the second statement is true.

c.Both statements are true.

d.Both statements are false

C

Evaluate the following statements:

I. Nonhydrolyzable tannins result from the condensation of catechin and leucocyanidin

II. Hydrolyzable tannins are called pyrogallotannins

III. Condensed tannins form a red insoluble polymerization product upon hydrolysis

IV. Pyrogallotannins are decolorized when subjected to the KMnO4 test

a.Only one statement is true

b.Two statements are true

c.Three statements are true

d.All statements are true

e.All statements are false

C

ALMOND OIL

a.Brassica napus

b.Elaeis guineensis

c.Carthamus tinctorius

d.Prunus dulcis

e.Oenothera biennis

D

Ethiodized Oil originally comes from

a.Oenothera biennis

b.Borago officinalis

c.Papaver somniferum

d.Brassica napus

e.Linum usitatissimum

C

PALM KERNEL OIL

a.Brassica napus

b.Elaeis guineensis

c.Carthamus tinctorius

d.Prunus dulcis

e.Borago officinalis

B

SAFFLOWER OIL

a.Linum usitatissimum

b.Elaeis guineensis

c.Carthamus tinctorius

d.Prunus dulcis

e.Borago officinalis

C

LINSEED OIL

a.Papaver somniferum

b.Elaeis guineensis

c.Carthamus tinctorius

d.Linum usitatissimum

D

Statement

I: Beeswax contains myricyl palmitate.Statement

II: Carnauba wax, a beeswax substitute, contains both myricyl palmitate and myricyl cerotate.

a.Both statements are false

b.Both statements are true

c.Only the first statement is true

d.Only the first statement is false

C

Fixed oils that can be used as vehicle for IM injections EXCEPT

a.Corn

b.Coconut

c.Arachis

d.Benne

e.Nota

B

CITRUS SINENSIS

a.sweet orange oil

b.roman chamomile oil

c.lemon oil

d.bergamot oil

e.cardamom oil

A

LAVANDULA ANGUSTIFOLIA

a.clove oil

b.lavender oil

c.cinnamon oil

d.star anise oil

e.bergamot oil

B

SYZYGIUM AROMATICUM (Eugenia caryophyllus

a.sage oil

b.peppermint oil

c.clove oil

d.star anise oil

e.anise oil

C

ELLETARIA CARDAMOMUM

a.chamomile oil

b.wintergreen oil

c.bergamot oil

d.cardamom oil

e.neroli oil

D

CITRUS AURANTIUM

a.eucalyptus oil

b.sweet orange oil

c.citronella oil

d.clove oil

e.bergamot oil

E

Give the chemical class of geraniol

a.phenol

b.aldehyde

c.ester

d.alcohol

e.hydrocarbon

D

Give the chemical class of pinene

a.ester

b.aldehyde

c.hydrocarbon

d.phenolic ether

e.oxide

C

Give the chemical class of thujone

a.hydrocarbon

b.oxide

c.aldehyde

d.ester

e.ketone

E

Give the chemical class of guiacol

a.phenol

b.alcohol

c.phenolic ether

d.ketone

e.ester

A

Give the chemical class of bornyl acetate

a.ketone

b.phenol

c.hydrocarbon

d.oxide

e.ester

E

Which is NOT mismatched?

a.Water Distillation: Spearmint

b.Expression: Lemon Oil

c.Steam Distillation: Clove Oil

d.Destructive Distillation: Turpentine Oil

e.Nota

B

Which of the following is correctly matched?

a.Labiatae: Trichomes

b.Umbelliferae: Oil Tubes Or Vittae

c.Pinaceae: Parenchymal Cells

d.Two Of The Above

e.Aota

D

Complex neutral substances devoid of characteristic chemical properties of resin and resin combinations

a.Resenes

b.Balsams

c.Glycoresin

d.Resinotannol

e.Nota

A

Podophyllum derivative used as a purgative

a.Podophyllin

b.Podophyllotoxin

c.Peltatin

d.A & C

e.A & B

C

The following are components of Compound Benzoin Tincture, EXCEPT

a.Benzoin

b.Aloe

c.Storax

d.Tolu Balsam

e.Nota

E

MYRRH

a.Resin

b.Oleoresin

c.Oleogum resin

d.Balsam

C

BALSAM OF COPAIBA

a.resin

b.oleoresin

c.oleogum resin

d.balsam

B

BENZOIN

a.resin

b.oleoresin

c.oleogum resin

d.balsam

D

CANNABIS

a.resin

b.oleoresin

c.oleogum resin

d.balsam

A

Which alkaloid class is mismatched with its amino acid source?

a.Quinoline: Tryptophan

b.Indole: Tryptophan

c.Isoquinoline: Tyrosine

d.Imidazole: Histidine

e.Nota

E

Alkaloidal reagent/s containing Iodine in Potassium Iodide

a.Wagner's reagent

b.Bouchdart's reagent

c.Marme's reagent

d.A and B

e.A and C

D

A mixture of morphine and cocaine used as analgesic in terminally ill cancer patients.

a.Paregoric

b.Laudanum

c.Apomorphine

d.Dover's Powder

e.Brompton's Cocktail

E

AUTUMN CROCUS (Colchicine)

a.isoquinoline

b.alkaloidal amine

c.xanthine

d.pyridine-piperidine

B

ABYSSINIAN TEA (Catha edulis-cathinone)

a.tropane

b.quinoline

c.alkaloidal amine

d.indole

C

KOLA NUTS (Caffeine)

a.tropane

b.purine

c.piperidine

d.imidazole

B

SNAKEROOT (R. Serpintina- Reserpine)

a.imidazole

b.quinoline

c.indole

d.isoquinoline

C

BLOODROOT(Sanguinarine)

a.purine

b.isoquinoline

c.quinoline

d.steroidal

B

Which of the following plants is correctly matched with its primary constituent?

a.C Alata: Allicin

b.V Negundo: Hydrolyzable Tannins

c.Q Indica: Quisalic Acid

d.E Microphylla: Menthol

e.P Pellucida: Camphor

C

The following are incorrectly matched EXCEPT

a.Bawang: Antihyperlipidemic

b.Bayabas: Astringent

c.Yerba Buena: Carminative

d.Tsaang Gubat: Stomachic

e.Aota

A

The only amino acid with a secondary amino group

a.Glycine

b.Proline

c.Phenylalanine

d.Arginine

e.Tryptophan

B

Which of the following tests will give a positive result for the amino acid precursor of catecholamines?

a.Pauly Test

b.Sakaguchi Test

c.Millons Test

d.Nitroprusside Test

e.Glyoxylic Acid Test

C

Which of the following amino acids are glucogenic?

a.Phenylalanine

b.Tryptophan

c.Alanine

d.A And B

e.Aota

E

What is the isoelectric point of an acidic amino acid that has the following pKa values:

pKa1 = 1.88

pKa2 = 9.68

pKa3 = 3.65

a.1.88

b.3.65

c.5.78

d.2.77

e.5.07

D

Level of protein organization characterized by multiple secondary units.

a.Secondary

b.Supersecondary

c.Tertiary

d.Quaternary

B

Which of the following specialized products is/are correctly matched with its amino acid derivative?

a.Melanin: W

b.Choline: Y

c.Histamine: S

d.No: R

D

State of nitrogen imbalance characterized by severe protein deficiency with a normal caloric intake.

a.Kwashiorkor

b.Marasmus

c.Primary Malnutrition

d.Secondary Malnutrition

A

Which of the following is a tetrose?

a.Ribose

b.Threose

c.Galactose

d.Glucose

B

Product of the reaction of glucose with HNO3 with a prior addition of a protecting group

a.Gluconic Acid

b.Gluconate

c.Glucaric Acid

d.Glucuronic Acid

D

Epimers show a difference only between ONE Chiral carbon.D-mannose is a C2 epimer of glucose.

a.Only The First Statement Is True

b.Only The Second Statement Is True

c.Both Statements Are True

d.Both Statements Are False

C

Which of the following is incorrectly matched in relation to their stereoisomerism with D-glucose?

a.D-galactose: Epimer

b.L-glucose: Optical isomer

c.D-mannose: Epimer

d.D-altrose: Anomer

e.D-fructose: Functional isomer

D

Which sugar will give a result of flower-like crystals when subjected to Osazone test?

a.Lactose

b.Sucrose

c.Fructose

d.NOTA

e.AOTA

B

Which sugar when tested for its identity will give the profile below:

Molisch: violet coloration

Fehling's: brick red ppt

Bial's: brown solution

Seliwanoff's: faint pink solution

Mucic Acid Test: soluble crystals

a.Glucose

b.Ribose

c.Fructose

d.Galactose

e.Trehalose

A

Which of the following saturated fatty acids is incorrectly matched with its number of Carbons?

a.Caproic: 8

b.Lauric: 12

c.Palmitic: 16

d.Arachidic: 20

A

What is the delta notation for OLEIC acid?

a.18: 1∆9<

b.18: 2∆9,12

c.18: 3∆9, 12, 15

d.18: 4∆9, 12, 15, 18

A

Special name for the autooxidation reaction that a lipid undergoes which produces foul smelling, short chain carboxylic acid as its breakdown products

a.Hydrogenation

b.Epoxidation

c.Rancidification

d.Saponification

C

Phospholipid with ethanolamine as its head group; has a role in blood clothing

a.Lecithin

b.Cephalin

c.Cardiolipin

d.Phosphatidylinositol

B

Which is matched correctly with its number of isoprene units?

a.Artemisinin: 4

b.Majority of Volatile Oils: 2

c.Vitamin A: 6

d.Squalene: 8

e.Paclitaxel: 3

B

Qualitative Test for Lipid used to specifically test for a phosphate group

a.Liebermann-Burchard Test

b.Acrolein Test

c.Osmic Acid Test

d.Ammonium Molybdate Test

D

Which of the following fixed oils is most likely to have an iodine value of 136?

a.Benne Oil

b.Sweet Oil

c.Linseed Oil

d.Peanut Oil

C

Five-carbon dicarboxylic acid

a.Suberic Acid

b.Azelaic Acid

c.Adipic Acid

d.Pimelic Acid

e.Glutaric Acid

E

A state where ketone levels are detectable in the blood.

a.Ketosis

b.Ketonemia

c.Ketoacidosis

d.Ketogenesis

B

I. Gaucher's disease, is the deficiency of glucosylcerebrosidase, is the most common lysosomal storage disease.

II. Tay-Sachs disease affects the beta hexosaminidase A enzyme.

III. Metachromatic leukodystrophy is a deficiency of the hexosaminidase A and B.

IV. Farber's disease, also known as lipogranulomatis, affects the enzyme alpha galactosidase.

Which of the statements above are true?

a.I, IV

b.I, II

c.I, II, III, IV

d.I, II, IV

B

Order the ff. statements regarding DNA replication consequentially

I. Attachment of DNA primase

II. Elongation of the DNA sequence via the DNA polymerase

III. Recognition of origin of replication

IV. Stabilization via the Single stranded DNA binding proteins

V. Unwinding via the DNA helicase

a.III-I-IV-II-V

b.I-III-V-II-IV

c.III-V-IV-I-II

d.I-III-V-IV-II

C

Splicing is a post-transcriptional process that removes exons while binding the remaining the intron portions. Either capping or polyadenylation is done to the spliced mRNA to produce a mature mRNA strand.

a.Only The First Statement Is False

b.Only The First Statement Is True

c.Both Statements Are True

d.Both Statements Are False

D

Which of the following serves as the Chain initiating sequence for the translation of prokaryotic mRNA?

a.Kozak

b.Shine-Dalgarno

c.Either

d.Both

B

Lesch-Nyhan syndrome, known as "juvenile gout", is a condition characterized by overproduction of uric acid coupled with neurological and behavioral abnormalities. What is the enzyme affected by this genetic condition?

a.Hypoxanthine Guanosine Phosphate Transferase

b.Hypoxanthine Guanine Phosphoribosyl Transferase

c.Hypoxanthine Guanine Phosphoribosyl Transaminase

d.Hypoxanthine Guanosine Phosphate Transaminase

B

Given the sequence AUGUCUUAUAGAGGGUAA, what mutation happens if the 3rd Uracil base is removed?

a.Frameshift

b.transversion

c.Point

d.transition

A

Given the sequence AUGUCUUAUAGAGGGUAA, what mutation happens when the last guanine in the sequence is replaced by adenine?

Note:

UCU: Serine

UAU: Tyrosine

AGA: Arginine

GGG: Glycine

GGA: Glycine

a.silent transition

b.silent transversion

c.missense transition

d.missense transverion

A

Most common form of DNA

a.A-DNA

b.B-DNA

c.Z-DNA

d.DNA-RNA Hybrids

B

Which enzyme catalyzes the substrate-level phosphorylation step?

a.V

b.W

c.X

d.Y

e.Z

C

Which of the following pathways takes place in a different part of the cell compared to the other choices?

a.oxidative phosphorylation

b.ketogenesis

c.fatty acid synthesis

d.TCA cycle

C

P. Gluconeogenesis is exactly like glycolysis, but in reverse.

H. Glycolysis is a cytosolic process that is stimulated by the insulin hormone during the fed state.

A. The most important enzyme in glycolysis is the Phosphofructokinase.

R. It is composed of two phases, the energy investment and energy payoff phase, with 6 steps and 4 steps, respectively.

M. Without oxidative phosphorylation, the net energy yield of glycolysis is 5 ATP.

a.one statement is correct

b.two statements are correct

c.three statements are correct

d.four statements are correct

e.all statements are correct

B

P. Pyruvate is converted to acetyl CoA and produces 5 ATP when acted upon by pyruvate dehydrogenase.

H. Anaerobically, pyruvate is converted to lactic acid by the lactate dehydrogenase with a loss of 5 ATP.

A. Pentose phosphate pathway is a consequent process to glycolysis which occurs in two phases--the oxidative and non-oxidative phase.

R. Gluconeogenesis, which occurs in the liver, converts non-carbohydrate substrates to glucose.

M. Pyruvate is converted to ethanol through a one-step conversion via pyruvate decarboxylase

a.one statement is correct

b.two statements are correct

c.three statements are correct

d.four statements are correct

e.all statements are correct

D

P. In the glycerol phosphate shuttle, the cytosolic glycerol-3-PO4 dehydrogenase converts glycerol-3-PO4 to dihydroxyacetone PO4.

H. In glycerol phosphate shuttle, the cytosolic glycerol-3-PO4 leads to the reduction of FAD to FADH2.

A. In the malate-aspartate shuttle, FADH2 is oxidized to FAD before the malate produced can enter the mitochondria.

R. In the malate-aspartate shuttle, oxaloacetate is converted to Aspartate in the mitochondria.

M. Malate-aspartate shuttle produces more ATP than the glycerol phosphate shuttle.

a.one statement is correct

b.two statements are correct

c.three statements are correct

d.four statements are correct

e.all statements are correct

B

P. Phenylketonuria is the first discovered aminoacidopathy.

H. Alkaptonuria, also known as "black urine disease", is manifested as crippling arthritis later in life.

A. The most common cause of albinism is an interruption in the functioning of the tyrosinase enzyme, which synthesizes melanin from Tyr.

R. MSUD is characterized by the buildup of amino acids V, I, and L, which block the brain transporters for other amino acids and thus lead to mental retardation.

M. All artificial sweeteners are contraindicated for phenyketonurics.

a.one statement is correct

b.two statements are correct

c.three statements are correct

d.four statements are correct

e.all statements are correct

C

Which of the following electron transport chain complex is mismatched with its inactivator?

a.Complex I: Rotenone

b.Complex Ii: Doxorubicin

c.Complex Iii: Antimycin

d.Complex Iv: Carbon Monoxide

e.Nota

B

Which of the following enzymes is/are involved in glycogenolysis?

a.Glycogen Phosphorylase

b.Alpha 1, 6 Branching Enzyme

c.Glycogen Synthase

d.Two Of The Above

e.Nota

A

Affects the lysosomal phosphofructokinase enzyme

a.Pompe's disase

b.Andersen's disease

c.Von Gierke's disease

d.Tarui's disease

e.McArdle's disease

D

Affecting the lysosomal alpha glucosidase enzyme, it is also known as "acid maltase deficiency"

a.Pompe's disase

b.Andersen's disease

c.Von Gierke's disease

d.Tarui's disease

e.McArdle's disease

A

End product of protein metabolism

a.Urea

b.Uric Acid

c.Blood Urea Nitrogen

d.Creatinine

A

Also known as the Embden-Meyerhof-Parnas pathway

a.Glycolysis

b.Pentose Phosphate Pathway

c.Tca Cycle

d.Lipolysis

e.Urea Cycle

A