Transcriptomics

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8 Terms

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What is the transcriptome?
set of all RNA transcripts (coding and non-coding)
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lncRNAs are transcribed RNAs from what enzymes?
RNA Pol I, II and III
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What is an example of a lncRNA?
* Xist
* Hotair
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TRUE OR FALSE? lncRNA is always capped and never polyadenylated.
FALSE.

* lncRNA is SOMETIMES CAPPED and SOMETIMES POLYADENYLATED
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What is the definition of lncRNAs?
RNAs longer than 200 nucleotides that are not translated into functional proteins
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What are some functions of lncRNAs?
* control of expression by affecting transcription
* affect chromatin biology
* involvement in splicing
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What is the function of lncRNA Xist?
* Regulation of X chromosome inactivation
* For silencing of one of the X chromosomes in female cell development
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What are circular RNAs?
single stranded RNA that forms a covalently closed continuous loop where the 3’ and 5’ ends have joined together