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What is plasmid extraction?
To remove the plasmid from bacteria
How big are plasmids?
Range in size from a few thousand to 50,000 bp
Where are plasmids present?
Present in many bacteria and a few eukaryotic cells
What do plasmids provide to bacteria?
Provide growth advantages to the bacteria
What is a selectable marker?
Identification of bacteria that contains the plasmid
What are shuttle vectors?
Plasmid that can be selected for, and stably maintained in both yeast and E.coli
What are some plasmid features in bacteria?
Resistance to an antibiotic such as ampicilin
How are plasmids replicated in yeast?
By an autonomously replicating sequence (ARSH4), and maintained with centromere (CEN6)
How is plasmid in yeast selected for?
By growing leu2 defective strains containing the plasmid in medium lacking leucine