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Flashcards on Embryology and Fetal Development
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Conceptus
Developing offspring
Gestation period
Time from last menstrual period until birth (~280 days)
Embryo
Conceptus from fertilization through week 8
Fetus
Conceptus from week 9 through birth
Cleavage
The stage of development with subsequent cell divisions following fertilisation.
Zygote
The fertilised egg.
Blastomeres
The cleaved cells.
Morula
A loose collection of blastomeres (little mulberry) by 72 hours after fertilisation.
Early blastocyst
About 100 cells which start to hollow out a cavity in the middle by day 4 or 5.
Blastocyst
Sphere made up of an outer shell of trophoblast cells and an inner cell mass.
Trophoblast cells
Outer shell of blastocyst, becomes the placenta.
Inner cell mass
Part of the blastocyst, becomes the baby and other tissues.
Epiblast and the hypoblast
forms a bilayer embryo when the inner cell mass becomes
Gastrulation
The two layered embryonic disk undergoes to become the three layered embryo (trilaminar embryo)
Ectoderm
Forms nervous system & epidermis
Mesoderm
Forms everything that ectoderm and endoderm do not. Forms Mesenchyme cells. The notochord immediately forms from this layer
Endoderm
Epithelial lining of digestive, respiratory and urogenital system and associated glands
Neurulation
Gives rise to brain and spinal cord
Fetal membranes
The amnion and chorion
Dizygotic twins
Two oocytes are released and fertilised (more common-1/100).
Monozygotic twins
One fertilised oocyte divides and becomes two embryos (3/1000).
Gestational age
Calculated from the last menstrual cycle so is approximately 14 days greater than fertilisation age or developmental age.
Full term
37-41 weeks
Preterm
Anything less than 37 weeks
SGA
Small for gestational age (below 10th centile).
AGA
Appropriate for gestational age.
LGA
Large for gestational age (Above 90th centile).
Fetal growth restriction (FGR)
Also known as intrauterine growth restriction (IUGR). a clinical definition not just a deviation from the normal weight. Must have clinical features of in utero growth retardation
Parturition
Culmination of pregnancy; giving birth to baby
Placenta
The central regulator of pregnancy outcome, regulates fetal growth through multiple pathways and therefore deficits in placental function is the primary cause of IUGR. Also must modulate maternal immune system to prevent rejection of fetus