Human Growth Hormone (hGH)

Underproduction

• Insufficient GH

• Results in TWO types of DWARFISM

What are the two types of dwarfism

1. Lorrain dwarfism

2. Frohlich’s dwarfism

Lorrain dwarfism

• Delayed SKELETAL, SEXUAL and MENTAL growth, alert, normal intelligence, normal body PROPORTIONS

• When other hormones and the GH are in SHORT SUPPLY

Frohlich’s dwarfism

• Short stature, slow SEXUAL development, sleepy

• Other endocrine activities are SLOW

GH therapy can restore and improve normal WHAT and WHAT

GROWTH and BODY FUNCTIONS

Overproduction

• TUMOUR or over activity of CELLS

• Results in TWO types of GIANTISM

What are those two types of giantism

1. Giantism in children

2. Acromegaly (in adults)

Giantism in children

• Increase in LENGTH of bones, OVERGROWTH of organs, tissues (heart, spleen)

Acromegaly (giantism in adults)

• Increase in bone THICKNESS, especially FACIAL features of NOSE + JAW, increase size of HANDS + FEET, skin is COARSE, increase in metabolic burn of SUGAR

Radiation therapy to destroy some WHAT

Overreactive TISSUES