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6.1 cell cycle
highly ordered sequence of events that take place in a cell. results in the division of the nucleus and the formation of 2 genetically identical daughter cells
6.1 interphase
growth period of the cell cycle between cell divisions (mitotic phase). consists of G1, S and G2
6.1 mitotic phase
cell division during the cell cycle. consists of mitosis and cytokinesis
6.1 senescent
cells that are permanently no longer able to replicate
6.1 checkpoint
control mechanisms of the cell cycle
6.1 kinase enzymes
enzymes that catalyse an addition to the phosphate group of a protein
6.1 cyclin
checkpoint proteins that can form cyclin dependent kinase complex (CDK)
6.1 phosphorylation
addition of a phosphate group to a molecule
6.1 tumour
an abnormal mass of cells
6.1 benign
non cancerous, slow growing tumours. they do not invade other tissues, but can cause damage
6.1 malignant
unchecked, uncontrolled, quick growing, cancerous tumour
6.1 telomeres
caps at the end of chromosomes, which get shorter at every replication
sets the hayflick limit
6.1 hayflick limit
where cells can only go though the cell cycle a certain number of times
6.2 asexual reproduction
the production of genetically identical offspring from a single parent cell
6.2 binary fission
asexual reproduction in prokaryotes, resulting in genetically identical offspring from one cell
6.2 mitosis
the nuclear division stage in the mitotic phase of the cell cycle
6.2 chromosome
condensed DNA wrapped around histones, which are only seen the mitotic phase and under a light microscope
6.2 chromatid
a sister chromatid after separation
6.2 centromere
un-replicated section of the chromosome where the sister chromatids are joined
6.2 prophase
first stage of mitosis when chromatin condenses to form visible chromosomes
the nuclear envelope breaks down
spindle fibres attach to centromeres and start to move chromosomes to the equator
6.2 metaphase
where chromosomes arrange in a single line along the equator of a cell
6.2 anaphase
spindle fibres contract and pull sister chromatids to opposite poles of cell
6.2 telophase
nuclear envelope and nucleolus reforms
chromosomes uncoil
becomes long and thin and uncondensed (chromatin)
6.2 cytokinesis
cell division phase of the cell cycle that results in the production of 2 identical daughter cells
6.2 cleavage furrow
a groove that forms on the surface of an animal cell during cell division
6.3 gametes
haploid sex cells produced by meiosis in organisms that reproduce sexually
6.3 zygote
diploid cell formed when 2 gametes are joined by sexual reproduction. it is the earliest stage of embryonic development
6.3 meiosis
a form of cell division where the nucleus divides twice, resulting in the halving of the chromosome number and 4 genetically unique haploid cells
6.3 haploid
half the normal chromosome number. one unpaired copy of each type of chromosome
6.3 reduction division
meiosis/cell division resulting in the production of haploid cells from a diploid cell
6.3 homologous chromosomes
matching pair of chromosomes, one inherited from each parent
6.3 diploid
2 copies of each chromosome
6.3 locus
position of a gene/allele on a chromosome
6.3 alleles
version/form of a gene
6.3 meiosis I
first version of two cell divisions, where a diploid parent cell divides to form 2 haploid cells
6.3 meiosis II
second stage of the 2 cell divisions, where the two haploid cells produced in meiosis I divide into 4 genetically unique daughter haploid cells
6.3 bivalents
a pair of a homologous chromosomes
6.3 crossing over/chiasmata
sections of DNA where chromosomes cross over each other and break off during anaphase 1, exchanging DNA between bivalent chromosomes.
results in the formation of recombinant chromatids and genetic variation
6.3 independent assortment
the arrangement of each homologous chromosome in metaphase 1 and metaphase 2 which are independent of each other and results in genetic variation
6.3 chiasmata
sections of DNA in chromosomes which cross over each other
6.3 recombinant
chromatids with new combinations of alleles/DNA
6.3 genetic variation
a variety of different combinations of alleles in a population
6.4 multicellular
multiple cells that are specialised and work together to perform functions
6.4 specialised
having particular structure to perform a specific function
6.4 differentiated
the result of differentiation - a specialised cell
6.4 erythrocyte
red blood cell
6.4 neutrophil
type of white blood cell that is phagocytic (ingests microbes and small particles)
6.4 tissue
group of cells that work together to perform a specific function/set of functions
6.4 squamous epithelium
tissue made form thin, flat squamous epithelial cells, which covers and lines free surfaces
6.4 ciliated epithelium
made of ciliated epithelial cells and goblet cells. it has hair like projections, which beat in a rhythm to move substances. it lines the oviduct and trachea
6.4 chondrocyte cells
mature, differentiated chondroblasts maintain the matrix in cartilage
6.4 cartilage
strong, flexible connective tissue found in joints, trachea, nose and ears
6.4 epidermis tissue*
single layer of closely packed cells, which cover the surface of plants
6.4 vascular tissue
transport tissue - composed of the xylem and the phloem
6.4 xylem tissue
plant transport tissue that carries water and minerals from roots to other part of the plant
6.4 phloem tissue
plant transport tissue that carries products of photosynthesis to all cells of the plant
6.4 organ
a group of tissues working together to perform a function
6.4 organ system
a group of organs working together to perform a function
6.5 differentiation
the process where unspecialised stem cells become specialised into different types of cell
6.5 undifferentiated
an unspecialised cell originating form mitosis or meiosis
6.5 stem cells
undifferentiated cells that are able to express all their genes and divide by mitosis
6.5 potency
the ability of stem cells to differentiate into different cell types
6.5 totipotent
a stem cell that can differentiate into any type of cell and form a whole organism and placental cells
6.5 pluripotent
a stem cell that can differentiate into any type of cell, but not from a whole organism and cannot form placental cells
6.5 multipotent
a cell that can only differentiate into a limited range of specialised cell types, within a certain type of tissue
6.5 bone marrow
tissue within bones which can contain multipotent cells which can differentiate into all types of blood cells
6.5 embryonic stem cells
undifferentiated cells from embryos that are pluripotent
6.5 adult stem cells
unspecialised, multipotent cells that are found in many organs of the body
6.5 meristematic tissue
tissue found at regions of growth in plants, contains meristem cells
6.5 meristems
plant stem cells - found at any growing point (e.g. roots) and sandwiched between xylem and phloem
6.5 blastocyte
a ball of cells formed in the early embryo
made of pluripotent cells and surrounded by stem cells which will develop into placenta and umbilical cord