MI unit 2 Test

What is a single gene disorder? Give an example

• caused by changes or mutations which occur in the DNA sequence of a single gene

• disease and disorder happens when a gene is mutated, resulting in a protein that can’t do its normal job

• Ex: Huntington is caused by a mutation of the gene Huntington which causes building blocks of DNA to repeat more times than normal

Why did those with the PTC taster allele have 2 or 3 bands and the nontasters only had one?

only taster alleles have a sequence the restriction enzyme can cut

what is a diagnostic test?

the patient has symptoms and the test is run to find the reason for those symptoms

what is a screening test?

looks to diagnose a condition or illness without symptoms present

what is the denaturing step of PCR?

this is the first step in PCR which

what does taq polymerase do in PCR?

it links the nucleotides together

during PTC lab, why did we use Haelll as the restriction enzyme?

its recognition sequence was found on one allele, but not the other

if a patient has gestational diabetes, what would happen