ANTIDOTE, REVERSAL AGENTS, AND RESCUE AGENTS

MEDICATIONS AND INDICATIONS

Activated charcoal

General poisoning/Overdose

Atropine sulfate inj

Nerve agents

Organophosphates toxicity

Dantrolene inj (Ryanodex)

Malignant hyperthermia

Deferoxamine mesylate inj

Iron poisoning

Digoxin immune Fab inj

Cardiac glycoside/Steroid toxicity

Flumazenil inj

Benzodiazepines toxicity

Zaleplon toxicity

Zolpidem toxicity

Fomepizole inj

Ethylene Glycol toxicity

Methanol toxicity

Glucagon inj

Beta blockers toxicity

Calcium channel blockers toxicity

Hypoglycemia

Hyaluronidase

Extravasation

Hydroxycobalamin inj (Cyanokit)

Cyanide Poisoning

Inhalation injury

l-carnitine inj

Valproate-induced hyperammonemia

Hepatic Dysfunction

Leucovorin

Methotrexate

Methanol

Lipid 20% emulsion inj

Highly lipophilic drug overdose induced cardiac arrest (LAST)

Methylene blue 0.5% inj

Methemoglobinemia

N-acetylcysteine oral (Mucomyst)

N-acetylcysteine 20% inj (Acetadote)

Acetaminophen Overdose

Naloxone inj

Opioid overdose

Unknown poisoning with mental status depression

Phentolamine

Extravasation of Vasoactive/Vasopressor agents

Physostigmine inj

Atropine and Anticholinergic Agents

Pralidoxime

Nerve agents

Organophosphates toxicity

Pyridoxine inj

Isoniazid toxicity

Hydrazine toxicity

MAOI toxicity

Sodium Nitrate/Sodium Thiosulfate

Cyanide Poisoning

Inhalation Injury

Calcium chloride inj

Calcium gluconate inj

Fluoride or Calcium channel blocking agent toxicity

Dextrose inj (D50 vials)

Hypoglycemia

Dextrose inj (D10 bags)

In combination with high-dose insulin therapy for beta blocking or calcium channel blocking agent toxicity

Folic acid inj

Methanol

Methotrexate

Ethanol

Glycopyrrolate inj

Neostigmine or pyridostigmine reversal

Organophosphate toxicity

Insulin, regular inj

Beta blocking or calcium channel blocking agent toxicity

Neostigmine

Reversal of non-depolarizing neuromuscular blocking agents

Octreotide

Sulfonylurea-induced hypoglycemia

Phytonadione (Mephyton)

Vitamin K antagonists

Protamine

Heparin reversal

Sodium bicarbonate inj

TCA overdose

Sugammadex

Reversal of neuromuscular blocking agents (rocuronium and vercuronium)

Thiamine inj

Prevention of Wernicke Encephalopathy

Dimercaprol inj (BAL)

Succimer cap (DMSA)

Lead toxicity

Arsenic toxicity

Mercury toxicity

Edetate calcium disodium (EDTA)

Lead toxicity

Glucarpidase

Methotrexate Toxicity

Uridine Triacetate

5-FU Overdose

Anti-Venom, Crotalidae (CroFab)

Anti-venom, Crotalidae equine immune F(ab’)2 (Anavip)

Crotalid or Copperhead envenomation

Anti-venom, scorpion (Anascorp)

Scorpion envenomation

Rabbies immune globulin

Rabbies Vaccine

Rabies post-exposure prophylaxis