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Properties of stem cells:
Undifferentiated -> differentiate -> specialised
Activates relevant ..., affecting .proteins ....
Affects cell shape, size, organelle numbers, structural adaptations
genes, synthesised
Sources of stem cells:
Embryonic:
Umbilical-cord blood:
Adult:
Induced pluripotent (iPs)
totipotent, pluripotent, multipotent, pluripotent
Induced pluripotent (iPs):
inserting certain genes into ... cells to become...
differentiated, undifferentiated
Ethical implications:
Killing embryo for stem cells
Embryos can't ... to use for research
Can't access pluripotency via...
consent, iPs
Potential uses of stem cells:
Bone marrow transplants
Can help cure ... ... by replacing bone marrow stem cells w donor's
Risk of rejection or donated stem cells ... and ... person's cells
blood cancer, differentiating, attacking
Potential uses of stem cells:
Repair of damaged tissue
Stem cells - repair/remake personalised tissues + organs from ... - help shape tissue/organ
iPs stem cells remove risk of...
scaffolds, organ rejection
Potential uses of stem cells:
Repair of damaged tissue
Stem cells - produce new neurons involved in ... release in brain - helps repair faulty neurons to regenerate ... ... in people suffering from ...
dopamine, muscle function, parkinsons
Potential uses of stem cells:
Drug research + development
Adult tissue stem cells in .... - can study development + model how medication can affect cells (... + ...)
organs, toxicity, efficiency
Potential uses of stem cells:
Drug research + development
Stem cells can produce ... ... which produce ..., - transplanted into diabetics to maintain ... ... ...
islet cells, insulin, blood glucose levels