The study of the effects of drugs on the body, specifically how a drug acts on its target to produce a biological effect.
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Pharmacokinetics
The study of how the body handles drugs over time, encompassing the processes of absorption, distribution, metabolism, and excretion (ADME).
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Adverse Drug Reactions (ADRs)
Unintended, harmful reactions that occur at normal doses of a drug, which can vary in severity and type among different patients.
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On-target side effects
Side effects that occur due to a drug's intended mechanism of action on its target receptors.
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Off-target side effects
Side effects that occur due to the drug acting on unintended targets that are not its primary site of action.
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Bioavailability
The proportion of a drug that enters the circulation when introduced into the body and is available for action.
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Half-life
The time it takes for the concentration of a drug in the bloodstream to reduce to half its original value.
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Drug interactions
Changes in the effect of a drug when taken together with another drug, food, or substance.
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Patient adherence
The extent to which a patient’s behavior corresponds with agreed recommendations from a healthcare provider.
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Prescribing Governance
Ensuring safety and accountability in issuing medication prescriptions to patients.
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Therapeutic Drug Monitoring (TDM)
The clinical practice of measuring specific drugs at designated intervals to maintain a constant concentration in a patient's bloodstream, optimizing their effectiveness and minimizing toxicity.