S & E Flowchart

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Decision Tree

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10 Terms

1
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Primary with Fast Nucleophile

SN2 if weak base

SN2 if strong base with E2 as minor pathway

2
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Primary with Slow Nucleophile

E2 if strong base

No reaction if weak base

3
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Secondary with Fast Nucleophile

E2 if strong base with SN2 as minor pathway

SN2 if weak base

4
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Secondary with Slow Nucleophile

E2 if strong base

E1 if weak base, polar protic, with heat

SN1 if weak base, polar protic, with no heat

5
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Tertiary with Fast Nucleophile

E2 if strong base

SN1 if weak base with polar protic

6
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Tertiary with Slow Nucleophile

E2 if strong base

E1 if weak base with heat

SN1 if weak base and no heat

7
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Tertiary Substrate

E1 & E2 & SN1

8
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Secondary Substrate

E1 & E2 & SN1 & SN2

9
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Primary Substrate

E2 & SN2

10
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Methyl Substrate

SN2