Rho Chi exam 3 questions

Which of these calcium channel blockers is best able to dilate coronary arteries?

a) Felodipine

b) Nitroglycerin

c) Verapamil

d) Diltiazem

a) Felodipine

CCBs have the highest affinity for the calcium channels in the ___ state.

a) Inactive state

b) Recovery state

c) Active state

d) Resting state

a) Inactive state

T/F: Alprostadil can cause an erection in the absence of cavernosal nerve stimulation

• true 

T/F: Clonidine reduces BP by acting in both the CNS and the periphery

• true 

Dobutamine is to atenolol as oxymetazoline is to:

a) Clonidine

b) Prazosin

c) Nadolol

d) Metoprolol

b) Prazosin

Patients deficient in N-acetyltransferase experience __ when

administered usual does of __.

a) Increased therapeutic effects; hydralazine

b) Increased adverse effects; hydralazine, minoxidil, or diazoxide

c) Reduced therapeutic effects; hydralazine

d) Increased adverse effects; hydralazine

d) Increased adverse effects; hydralazine

Mechanisms to reduce the production of aqueous humor include:

a) Activation of muscarinic and alpha-2 receptors

b) Activation of alpha-2 receptors and inhibition of beta-2 receptors

c) Inhibition of beta-1 receptors and activation of alpha-2 receptors

d) Activation of alpha-2 and beta-2 receptors

b) Activation of alpha-2 receptors and inhibition of beta-2 receptors

Which of the following is NOT an adverse effect of aliskiren?

a) Hypokalemia

b) Fetopathic

c) Angioedema

d) Low blood pressure

a) Hypokalemia

T/F: Clevidipine is more likely to cause reflex tachycardia, therefore you should co-administer beta-1 blockers with it

• true 

Which of these drugs stimulates the formation of cyclic GMP?

a) Treprostinil

b) Riociguat

c) Macitentan

d) Sildenafil

b) Riociguat

Nitroprusside releases nitric oxide by vascular ADH2, and only dilates arterial vessels

a) First half of the sentence is true, and the second half is also true

b) First half of the sentence is not true and the second half is also not true

c) First half of sentence is true but the second half is not true

d) First half is not true but the second half is true

b) First half of the sentence is not true and the second half is also not true

SATA: Which drug is converted into a pharmacologically active

compound inside the body?

a) Midodrine

b) Enalaprilat

c) Losartan

d) Nitroglycerin

a) Midodrine

c) Losartan

d) Nitroglycerin

Norepinephrine administration leads to an increased total peripheral resistance, and a decreased heart rate

a) First half is true, second half is true

b) First half is true, second half is false

c) First half is false, second half is true

d) First half is false, second half is false

a) First half is true, second half is true

Which CCB would be best if the patient required strong negative chronotropic, dromotropic, and negative inotropic effect

a) Diltiazem

b) Verapamil

c) Amlodipine

d) Nifedipine

b) Verapamil

What would be the effect of a patient infused with Angiotensin II?

a) Decreased TPR, Decreased HR

b) Decreased TPR, increased HR

c) Increased TPR, decreased HR

d) Increased TPR, Increased HR

c) Increased TPR, decreased HR

SATA: Which of the following contribute to the dry cough seen with ACE inhibitors?

a) Decreased Angiotensin II

b) Increased Bradykinin

c) Increased Prostaglandins

d) Thromboxane A2 Blockade

b) Increased Bradykinin

c) Increased Prostaglandins

Which of the following is fetopathic?

a) Latanoprost

b) Nitroglycerin

c) Lisinopril

d) Entresto

c) Lisinopril

Which of the following is not an ADR of nitrates?

a) Flushing of skin

b) Headache

c) Rash

d) Diarrhea

d) Diarrhea

Which of the following can be used during pregnancy?

a) Lisinopril

b) Olmesartan

c) Aliskiren

d) None of the above

d) None of the above

ACE inhibitors can cause hypokalemia and angioedema

a) The first half is true, and the second half is also true

b) The first half is false, but the second half is true

c) The first half is true, but the second half is false

d0 The first half is false, and the second half is false

b) The first half is false, but the second half is true

SATA: Which of the following can be used to treat glaucoma?

a) Carboprost

b) Dinoprost

c) Travaprost

d) Tafluprost

c) Travaprost

d) Tafluprost

Which of the following drugs can be used with Verapamil?

a) Atenolol

b) Nifedipine

c) Lisinopril

d) Digoxin

c) Lisinopril

Inhibition of which of the following causes Levitra to have blue-green vision?

a) PDE-5

b) PDE-6

c) PDE-3

d) Levitra does not cause blue-green vision

b) PDE-6

T/F: Epinephrine has greater affinity to alpha-1 receptors compared to Norepinephrine

false