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physiology is
the science of HOW the body works
proper functioning of one part depends on?
the function of a different part or parts
levels of organization in the body
cell, tissue, organ, organ system, organism
cells are classified into four groups:
neurons, muscle cells, epithelial cells, connective tissue cells
neurons transmit signals for
communication
multipolar neurons have
multiple dendrites and one axon
unipolar neurons have
short single process leaving the cell body
muscle cells are specialized to
contract
muscle cells can be
voluntary or involuntary
epithelium is
a sheet-like layer of cells
epithelium lines
EXTERNAL body surfaces
epithelium lines
hollow organs or vessels (like the lumen)
epithelium functions as
a barrier and a transport membrane
glands are formed by
epithelium
exocrine glands
have ducts and secrete sweat or salivary
endocrine glands
have no ducts and are inside; like hormones
the most diverse of the four tissues
connective tissue
connective tissue is characterized by
extracellular matrix
connective tissue:
anchors and links structures of the body like bones and tendons
examples of external environment
- air in the lungs
- urine in the bladder
- food in the stomach
the internal environment is
the immediate environment of most cells
interstitial fluid is
fluid around all cells other than blood cells
plasma is
fluid around blood cells
exchange between blood & external environment happens in
- lungs
- gastrointestinal tract
- kidneys
kidneys have reabsorption why?
because it was filtered in the beginning
sodium increases
blood pressure
TBW
means total body water
TBW contains
- water & dissolved materials
- intracellular fluid
- extracellular fluid
total body water is
ALL of the fluids
intracellular fluid means
fluid inside cells
extracellular fluid means
fluid outside cells but within the body
extracellular fluid is considered the
internal environment
subdivisions of extracellular fluid
plasma and interstitial fluid
what percent of your total body weight is TBW
60%
physiology is
the maintenance of constant internal environment of your body in an external variable condition
to maintain homeostasis
it requires organ system integration (working together)
regulated variable means
the aspect that is maintained during homeostasis
set point means
the expected value of a regulated variable (blood ph, body temp)
the error signal in homeostasis is..
difference between the value of the set point and the value of the regulated variable
negative feedback during homeostasis
- is an on and off system
what structures enable homeostasis
receptors (detection), integrating centers, effectors, signals
what organ is the integrating center for the whole body
the CNS
integrating centers..
orchestrates an appropriate response
afferent signal is
the message that your receptor will detect and send to your brain
efferent signal is
the signal that is sent to the effector
positive feedback is
on until the job is done
what is metabolism?
sum of all chemical reactions in the body
reactants or substrates come together to make
a product
catabolic reactions
breakdown of larger molecules into smaller ones
anabolic reactions
build up large chemicals and require energy
storing is considered
anabolic
types of metabolic reactions
Hydrolysis & Condensation
Phosphorylation & Dephosphorylation
Oxidation & Reduction
Hydrolysis is a _______ reaction.
catabolic
condensation is a ____ reaction
anabolic
hydrolysis
the chemical breakdown of a compound due to reaction with water.
condensation
The change from a gas to a liquid
phosphorylation
The metabolic process of introducing a phosphate group into an organic molecule.
dephosphorylation
removal of a phosphate group from a molecule
oxidation-reduction
Also known as redox; a chemical reaction in which the oxidizing agent is reduced (by losing oxygen) and the reducing agent is oxidized (by gaining oxygen).
Which of the following is the smallest living unit of the
body?
cells
Which of the following is NOT an epithelial
structure?
the sciatic nerve
The protein X is only detectable inside the glial cells. Why is protein X not also detected in the extracellular
fluid?
The glial cell membrane is not permeable to protein X, and it is not actively transported out of the cell.
Homeostasis is a term which describes the process whereby the body
maintains a constant internal environment.
Which of the following does NOT describe a part of post-transcriptional
processing?
formation of bonds between a phosphate group and a sugar
The process whereby a complementary mRNA is produced from a DNA template is
called
transcription
Which of the following components of the plasma membrane forms ion
channels?
transmembrane proteins
Which of the following is NOT an integral membrane
protein?
actin
Which of the following is NOT an amphipathic
molecule?
glucose
positive feedback
A physiological control mechanism in which a change in some variable triggers mechanisms that amplify the change.
negative feedback
a mechanism of response in which a stimulus initiates reactions that reduce the stimulus (maintains homeostasis)
cells are derived from
the fertilized ovum
plasma membrane separates
the cell and the external environment
cytoplasm is
everything within the cell including the organelles, but not the nucleus.
cytosol is
the liquid portion within the cell, not including the organelles.
the plasma membrane is
a phospholipid bilayer surrounding the cell
hydrophilic means
Attracted to water
Hydropholic means
water loving
plasma membrane is important to
barrier to passage of water-soluble substances
lipid soluable also means it is
non-polar, lipophilic, & hydrophobic
h2o soluable also means it is
polar, lipophobic, & hydrophilic
if the receptor is on the cell surface of the cell membrane that means
it is water soluble
if the receptor is on the inside of the cell membrane that means
it is lipid soluble
aquaporins are
Water channel proteins that provide cell membrane permeability to water.
cholesterol adds ____ to the cell membrane
fluidity
cholesterol
interferes with hydrophobic interactions between phospholipids
amphipathic
having hydrophilic and hydrophobic parts
examples of transmembrane proteins
channels and carrier proteins
differences between channels and carrier proteins
-channels do not require energy, carriers do
-channels are faster transport, carriers are slower
-channels are for small materials, while carries are larger materials
voltage-gated means
if you change the volt, it will open the gate of the channel
receptors are
easily dissociated from the cell membrane
carbohydrates
are covalently bound to membrane lipids or proteins
nucleolus is the site of
ribosomal RNA synthesis
nucleus is
the site of all genetic information & DNA
chromatin helps
DNA molecules packs inside the nucleus as chromosomes
function of cytosol
distributes materials by diffusion; stores glycogen, pigments, and other materials
membranous organelles are
covered with plasma membrane, isolated from cytosol
non-membranous organelles are
not enclosed by a membrane and always in touch with the cytosol.
endoplasmic reticulum function
Transport channels in the cell
-transports synthesized proteins and lipids to other parts of the cell
golgi apparatus function
modifies, packages, stores, and transports lipids made by Smooth ER
mitochondria function
powerhouse of the cell, ATP production