BIMM112 - Final - Histone Modifications

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12 Terms

1
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H3K4me3 + found where?

activation, in promoters

2
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H3K36me3 + found where?

activation, in gene bodies/transcribed regions of active genes

3
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H3K9me3 + bound by? + found where?

repression, HP1, heterochromatin

4
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H3K27me3 + bound by?

repression, PRC1 (reader to trigger repression) and PRC2 (reader/writer)

5
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H3K4 methylation essential for viability of budding yeast?

No

6
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H3K4 methylation essential for transcriptional regulation of fruit flies?

No

7
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H3K6me3 + found where?

activation, in promoters

8
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H3K79me3

activation

9
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two active transcriptional enhancers

H3K4me1, H3K27ac

10
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Su(var)2-5

encodes heterochromatin protein 1-alpha (aka. HP1a)

11
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Su(var3-9)

encodes H3K9 methylated which gets bound by HP1

12
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H3K27ac

activation, in enhancers