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recovery model
sees relapse as part of the process and an opportunity for progress
ADH and ALDH
enzymes that break down all into acetaldehyde → toxic byproduct that causes a hangover
liver
alcohol is metabolized in the ___ by enzymes
antabuse
behavioral deterrent of etoh
-makes you super sick after alc consumption
etoh effects
-CNS depressant
-euphoric effect caused by GABA
-resp depressant
-decreased balance, reflexes, judgement
-blackouts/amnesia
-alc hallucinosis, DTs, encephalopathy
alcoholic hallucinosis
hallucinating
-ego dystonic → terrifying
-support pt and be there for them
DTs
severe alc withdrawal
-acute delerium
-tremors, agitation, hallucinations
-diaphoresis, hyperthermia, tachycardia, HTN
-tx: benzos and supportive care
wernicke’s encephalopathy
sudden, severe brain disorder
-acute confusion, muscle loss, ataxia, visual vhanges
-thiamine deficiency → give vit B1/thiamine
-can be reversed
korsakoff’s syndrome
permanent change from chronic etoh use
-cannot create new memories
-preventable form of dementia
esophageal varices
esophageal veins distended dt increased pressure from defective blood flow thru cirrhotic liver
-portal HTN
-GI hemorrhage
alcoholic myopathy
degenerative changes of heart and skeletal muscles
-CPK elevations
-acute sxs: sudden onset of extreme muscle pain, edema and weakness in extremities, reddish tinged urine
-long termL cardiomegaly
acute alcoholic pancreatitis
constant, severe, left-sided epigastric pain
-N and V
-may become chronic
peripheral neuropathy
pain and numbness
-tingling, burning in extremities
benzodiazepines
mimic etoh and decrease excitatory response, anti convuslant, increase GABA
-CNS and respiration depression risks
-taper off
-ativan and clonidine
-front loading
naltrexone
decreases cravings
ativan and clonodine
popular benzos
opiate fx
pain suppression, pinpoint pupils, lowered HR, BP, resp rate, constipation, cough suppression, lax muscle tone, dry mouth
-withdrawal has opposite fx
opiate withdrawal
yawning, fever, muscle aches and pain, insomnia, dysphoric mood, N and V and D, rhinorrhea, pupillary dilation, diaphoresis
opioid detox
tylenol PRN for pain, OTC anti diarrheal, anti emetics for N and V (zofran), ativan PRN for anxiety, clonidine - antihypertensive and help w/ withdrawal sxs
-chronic methadone use, naltrexone to decrease cravings, naloxone for OD
-counseling and bx therapies
medication assisted tx for opioid
methadone
-buprenorphine + nalaxone: partial opioid receptor blocker, help control cravings, reduce withdrawal
stimulants
CNS activation, increased DA, increased NRG, decreased appetite/thirst, increased reflexes, HR, BP, breathing w/ cardiac risks
-hypersensitivity, dilated pupils
withdrawal of stimulants
depression, irritability, anergia, anhedonia, increased risk for depression, SI, or bx
cocaine/meth risks
cardiac artery restriction → heart arrhythmias
-MI
-increased cardiac demand, HR → acute chest pain and severe vasoconstriction
wellbutrine
antidepressant that can be used as meth and cocaine tx along with
-supportive care
-12 step
-sleep, dental, nutrition, infections
not
meds are __ required for stimulant withdrawal/detox