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circulatory system and integumentary system
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tunica intima
inner most lining, flattened epithelial cells supported by connective tissue, capillaries only have this and basement membrane
tunia media
middle layer, contains smooth muscle cells, most variable thickness determining size of lument and therefore differentiates blood vessels
tunica adventitia
outermost connective layer in vessels
large elastic arteries
conducting and maintaining smooth flow of blood with elastic layers
medium musclar arteries
distributing, circular smooth, involuntary muscle fibres, can reguate blood through vasoconstriction
small arteries and arterioles
narrow lumen, thick smooth muscle walls, continuous slight contraction to regulate arterial pressure
pulsatility
arteries are pulsatile and have high blood pressure reflecting systole and diastole
anastomoses
linking between adjacent arteries, providing collateral flow if path is blocked, more often around joints eg. knee
collateral flow
alternate flow of blood in anastomoses
end arteries
arteries with no anastomoses but still drain into capillary veins
venae comitantes
multiple veins wrapped around artery
medium veins
drain venous plexuses, valves, named according to artery
venule and small veins
drain into venous plexuses, no valves, only tunica intima
large veins
wide bundle of longitudinal smooth muscle, well developed tunica adventitia
valves
folds of the endothelium into cusps, preventing backflow of blood, often distal to the entrance of major tributary
capillaries
simple endothelial tubes, number of beds vary according to body region
tone
continuous partial contraction of vacular smooth muscle
visceral motor nerves, specifically vasomotor nerves
nerves that coordinate blood flow through vasoconstriction
vascular venous pumps
a result of venae comitantes, connective tissue around prevents expansion so blood in veins is pumped back
musculovenous pumps
main method of venous return, expansion of msucle pump veins, but consider that they are limited by fascia
thoracic venous pump
double pump system where the heart is connected to the diaphram — SVC on top IVC on the bottom
3 tunics, thinner wall in veins, valves, more numerous than veins, facilitated by smooth muscle contraction (media)
characteristics of the lymphs
lymph nodes
filter to drap particles, defend against foreign antigens, slow flow, cluster where there is high risk of infection
right lymphatic duct of the thoracic duct
2 main ducts of the lymph system
internal jagular joints the subclavian vein
the spot where the lymph drain into the venous system
right jugular trunk, right subclavian trunk, right lymphatic duct
path of the lymph from right head, neck, upper limb, thorax and abdominal
left jugular trunk, left subclavian trunk, thoracic duct
path of the lymph from the rest of the body
epidermis
avascularised outtermost layer of the skin comprised of epithelial cells
dermis
vascularsied, deeper layer of conncetive tissue
hypodermis
subcutaneous layer under the skin
stratum basale
deepest layer of the epithelium, one layer of active stem cells
stratum spinosum
prickly layer, several layer of keratinocytes, the 4th layer from the top
stratum granulosum
granular, 1-5 layers of flattened cells, the 3rd layer from the top
stratum lucidum
clear layer, 2nd layer from the top, not present in thin skin
stratum corneum
superficial layer, mostly dead cells, thickest of the epidermis layers
melanocytes
cells in the basal layer that produce melanin
keratinocytes
cells of the skin
thick skin
hairless, thicker stratum corneum
thin skin
hairy, no stratu lucidum, other strata thinner
papillary layer
1/5 of thickness of dermis, has capillaries and sensory receptors, forms dermal ridges on skin
papillary layer + dermal ridges
layer of dermis + thing that produces the finger and footprints
reticular layer
deeper layer of dermis, attatched to hypodermis, collagen fibre create cleavage/tension lines, has vessles, nerves, hair follicles, sebaceous and sweat glands
reticular layer + cleavage/tension lines
dermis layer + thing that means wound gape
shared mesoderm origin
why is the dermis vascularised but not epidermis
diffusion through interstitial fluid
how does epidermis get nutrients and get rid of waste
subcutaneous tissue
superficial fascia, loose connective tissue of variable thickness under skin
septa
fibrous strands that bind subcutaneous tissue to underlying dense connective tissue especially at palms, soles and scalp
medulla, cortex, cuticle
3 layer of the hair
medulla: not in thinner hair, 2-3 rows of irregular cells
cortex: elongated cells
cuticle: singler layer of thin fat cells
accessory pili muscle
pulling the hair up, sympathetic nervous system
keratinised epidermal cells
what are nails made of
nail plate, nail bed, subungual dermis, periosteum
the chain from nail plate to periosteum that is connected
subungual dermis is thick and highly vascular
lunule
part of the nail where new nail cells are developing, pooly vascularised
sebaceous glands
connected to hair follicles, produces sebaceous substances
sweat glands
release sweat into hair follicles or skin via pores
ceruminous glands
modified sweat glands that produce ear wax
dermatome
the area of the skin supplised by one spinal cord nerve, due to segmental innervation. due to somites dragging skin with it as it develops into organ buds
referred pain
somatic area supplied by the same dermatome as the deeper organs
stretch marks
lateral bonding between collagen fibres is broken andd breaks small blood vessels
burn epidermis only
1st degree burn
burn epidermis and 1st layer of dermis
2nd degree burn
burn the full thickness of the skin
3rd degree burn
due to catastrophic loss of body fluids
why do burns result in death?