Week 7 Quiz Flashcards

What is a double-blind trial?

A trial where neither the patient nor the doctor knows who is receiving the drug and who is receiving the placebo

Sort the pieces of evidence into the HIGHEST (1) quality to LOWEST(5) quality when evaluating clinical interventions

1. Meta-analysis

2. RCT ( randomised controlled trial)

3. Case Report

4. Animal Study

5. Protein-Drug Assay

What are the steps for evidence-based practice?

1. Formulate a clinical question

2. Collect evidence to answer the clinical question

3. Critically assess the evidence and the method of collection

4. Apply the evidence collected to patient care

5. Reflect on the process and outcomes

What does mRNA do?

Encodes protein

What does tRNA do?

Decoded the genetic code

What is true of ribosomes?

They are found both free in cytoplasm as well as bound to membranes e.g RER

What is A and B called in the diagram on the flipside?

Where do Paracrine agents act?

They act locally on nearby cells

In what order does blood flow from the heart and then return to it?

1. Artery

2. Arteriole

3. Capillary

4. Venue

5. Vein

What are cells that directly regulate constriction of blood vessel arterioles known as?

SMOOTH muscle cells

What are cells that secrete hormones into the circulation system known as?

Endocrine cells

What are cells that support neurones in the Central & Peripheral Nervous system known as?

Glial Cells

Why does intestinal epithelial cells provide a high surface area for passive diffusion processes?

• Through the presence of apical microvilli

Determine the hybridisation state of the Nitrogen atom in each of the heterocyclic molecules

Sp2, sp3, sp2

Count the number of π electrons in the following cyclic structures

1. 6

2. 10

3. 10

4. 10

5. 4

What are the following requirements for a molecule to be considered ANTI-aromatic?

• Must be planar

• Must have a 4n number of π electrons

• Must be cyclic

• Must be completely conjugated

Memorise then flipside of this flashcard

In your community pharmacy you are running a campaign to increase awareness of unhealthy alcohol consumption. A customer has seen the information in your window and comes in for advice, as they are aware they consume more alcohol than recommended. During the discussion the customer says they would like to cut down, as they don’t want to damage their liver, but their main social life is as a member of the local pub quiz team, where it is expected that they have several drinks after the end of each match.

At which stage of the transtheoretical model of behaviour change is this customer?

Contemplation

How many minutes of moderate exercise are recommended fir healthy older adults (65 and over) each week

150 minutes

What do all molecules possess?

A basic framework consisting of sigma bonds.

What can molecules with sp2 hybridised atoms do?

Form pi bonds

What bonds does conjugation occur with?

Alternating single and double bonds

How does the following Flashcard relate in orbital terms?

In orbital terms, it requires a continuous array of sp2 or sp hybridised orbitals containing an unhybrisided p orbital. These orbitals can overlap to create an extended pi orbital

Describe the following 5-membered rings