4/5 of dermis; made up of dense irregular CT (prevents stretching and tearing)
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reticular
(dermis) reticular and elastic fibers to allow the skin to stretch
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reticular
(dermis) its protein fibers provide strength, extensibility and elasticity
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reticular
(dermis) includes many accessory organs within or have them extending through
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papillary
1/5 of dermis, superficial (outer)
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papillary
(dermis) areolar with lots of elastic fibers
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dermal papillae
finger-like projects that extend towards the epidermis and strengthens the connections between layers
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papillary
(dermis) creates contours in the surface called friction ridges (fingerprints)
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papillary
(dermis) contains touch receptors and free nerve endings sensing pain
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Meissner's corpuscles
sensitive touch receptors in the dermis
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Clevage (tension) lines
elastin and collagen fibers oriented in some directions more than in others (important in surgery)
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parallel
if incision is made _________________ to lines, there is less gapping, faster healing and less scar tissue
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dermal tears
skin is overstretched, striae (stretch marks) occur
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epidermis
is in a continual state of regeneration (mitosis)
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epidermis
cells form a waterproof, protective wrap over the body's surface
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epidermis
avascular because it's nourished by diffusion from capillaries of the papillary layer of the dermis
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basement membrane
separated from the dermis by the __________________________________
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the epidermis renews itself every ____________ days
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keratinocytes
(epidermis) most cells, produce keratin for strength and waterproofing
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melanocytes
(epidermis) cnotribute to skin color; prevent DNA mutation from UV radiation
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freckles, moles
accumulation of melanin forms ________________ and ________________.
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Langerhan's Cells
(epidermis) part of the immune system
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Merkel's Cells
(epidermis) detect light, touch, and superficial pressure
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desquamate
cells of the deeper layers undergo mitosis; as they move toward the surface, older cells slough off
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keratinization
as cells move outward through the layers, they fill with keratin, die, and serve as a layer that resists abrasion and forms permeability
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corneum, lucidium, granulosum, spinosum, basale
List the 5 layers of the epidermis in order from surface to deep (neglect the word stratum).
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stratum basale
deepest portion of the epidermis and single layer of columnar cells
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stratum basale
high mitotic activity
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stratum basale
cells become keratinized
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stratum spinosum
multiple layers of cuboidal cells with limited cell division
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stratum spinosum
desmosomes - molecular bridges that connect them to adjacent cells giving them a spiny appearance
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stratum spinosum
contains Langerhans macrophages
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stratum granulosum
also contains Langerhan's; 3-5 rows of partially flattened cells containing small protein granules - keratohyalin (helps with keratin)
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stratum granulosum
in superficial layers nucleus and other organelles degenerate and cell dies
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stratum lucidum
found only where "thick skin" is like the palms and soles
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stratum lucidum
3-4 rows of flattened, dead cells that are mostly transparent (ghosts_ and completely keratinized; thin clear zone
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stratum corneum
most superficial layer; 20-50 rows of flattened, dead cells that are continuously being sloughed off
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stratum corneum
consists of cornified cells (dead cells containing an envelope filled with soft keratin)
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stratum corneum
tough, waterproof protection from this epidermal layer
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3-4 weeks
How long does it take for cells produced in the stratum basale to migrate to the surface and be sloughed off
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impermeable
the keratin barrier is NOT ____________________-
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softens
after soaking keratin in water for a long period of time, it ______________________, making it more permeable to water; water leaves cell and skin appears temporarily wrinkled
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thick skin
what type of skin has all 5 epidermal layers
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thick skin
this type of skin is found in areas subject to pressure or friction likes the palms, soles, and fingertips
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thick skin
the papillae of the underlying dermis are in parallel rows that shape the overlying epidermis into fingerprints and footprints
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thin skin
more flexible of the two skin types, covers the majority of the body (local response to friction and pressure)
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callus
increase in number of layers in the stratum corneum; when this occurs over a bony prominence, a corn forms
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skin color
What is determined from pigments, blood circulating through skin, and thickness of the stratum corneum?
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melanin
provides for protection against UV light; colored brown to black, may be yellowish or reddish
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melanocytes
a mature melanin-forming cell; processes extend between keratinocytes
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albinism
a recessive genetic trait resulting in a deficiency or absence of pigment; production determined by genetics, hormones, and exposure to light
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hemoglobin
red, oxygen carrying pigment in erythrocytes (RBCs)
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carotene
yellow pigment; from vegetables; accumulates in stratum corneum, in adipose cells of dermis and hypodermis
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blood
imparts a reddish hue and increases during blushing, anger, inflammation
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cyanosis
blue color caused by a decrease in blood-oxygen content
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decubitus ulcer
bedsores, blood flow is restricted where the body has constant pressure on bed; cells die
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dermis
For tattoos to be permanent, what layer must the ink be injected into?
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hair
What is found everywhere on the body except for palms, soles, distal segments of fingers, etc.?
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shaft
portion of the hair that protrudes above the skins surface
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root
portion of the hair located below the surface; lies within the follicle
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medulla
central axis of the hair
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cortex
forms bulk of hair, middle layer
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cuticle
forms the hair's surface
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hair follicle
dermal root sheath and epithelial root sheath make this up
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dermal root sheath
part of dermis that surrounds the epithelial root sheath
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epithelial root sheath
sheath with internal and external parts
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internal
In/external portion of epithelial root sheath contains the stratum basale that may remain after injury and supply a source of new epidermis?
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white bulb
when hairs are pulled out, the internal part comes out and is visible as a _______________________
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hair bulb
contains internal matrix of the hair and the dermis projects into it
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internal matrix
part of the hair bulb that is the source of hair growth
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blood supply
dermis projects into the bulb and is the _____________________
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hair growth
is influenced by nutrition, hormones, and blood flow
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growth
hair stage where cells are added at the base and hair elongates (avg. rate is 0.3 mm/day)
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rest
hair stage where the follicle shortens and holds hair in place, then the hair falls out of the follicle and new hair begins
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permanent hair loss
pattern baldness is the most common cause for this
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hair color
What is caused by varying amounts and types of melanin?
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melanin
What pigment can be black, brown and red?
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dark
What color(s) is hair that contains true melanin?
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blonde, red
What color(s) is hair whose melanin contains iron and sulfur?