Antibody Classes and Domains
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10 Terms
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Name the five antibody classes?
IgM, IgD, IgG, IgA, IgE
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What determines antibody isotype?
Heavy chain constant region
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How many domains does a light chain have?
Two
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How many domains does a heavy chain have?
Four or Five
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How many amino acids per Ig domain?
~10
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What structural feature stabalises Ig domains?
Disulfide bridges
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What protein family do antibodies belong to?
Immunoglobulin superfamily
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What differs between antibody isotypes?
Structure and function
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What determines interaction with complement?
Constant heavy (CH) regions
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What determines interaction with Fc receptors?
Fc region
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