citric acid cycle

step 1

formation of citrate

what catalyzes step 1

citrate synthase

what is citrate synthase inhibited by

atp

what is citrate synthase activated by

ADP

step 2

isomerazation

isomerazation

tertiary alcohol converted to secondary alcohol

oxidation and decarboxylation

secondary alcohol becomes ketone

step 3

oxidation and decarboxylation

what is lost and formed in oxidation and decarboxylation

Co2 lost

nadh formed

what is oxidation and decarboxylation catalyzed by

isocitrate dehydrogenase

isocitrate dehydrogenase is inhibited by

nadh

step 4

decarboxylation and oxidation

what is lost and formed decarboxylation and oxidation

Co2 lost

Nadh formed

what is decarboxylation and oxidation catalyzed by

alpha ketoglutarate dehydrogenase complex

what is important ab step 4

irreversible

step 5

hydrolysis

hydrolysis

GTP is produced

step 6

oxidation

oxidation

alkane portion converts to alkene

what is formed in oxidation step 6

fadh

step 7

hydration

hydration

alkene converts to alcohol

step 8

oxidation

oxidation step 8

alcohol converts to ketone

what is produced in step 8

nadh

by products of citric acid cycle

3 nadh

1 fadh2

1 gap