Irbesartan
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10 Terms
Irbesartan
Avapro
Irbesartan drug class
Angiotensin II Receptor Antagonist
Irbesartan dosage form
oral: tablet
Irbesartan ON label indications
1. Diabetic nephropathy
2. HTN
Irbesartan OFF label indication
1. Left ventricular hypertrophy
2. HTN, renal impairment
Irbesartan MOA
selective, reversible, competitive antagonist of angiotensin II receptor (AT1), which is responsible for the physiologic effects of angiotensin II including vasoconstriction, aldosterone secretion, sympathetic outflow, and stimulation of renal sodium reabsorption
Irbesartan box warning
pregnancy
Irbesartan contraindication
Hypersensitivity or pregnancy, concomitant use with aliskiren in diabetics
Irbesartan pregnancy/breastfeeding
Human data suggest risk in 2nd and 3rd trimesters/probably compatible
Irbesartan adverse effects
Hyperkalemia
Note 
Flashcards (355)