alzheimers

what are symptoms of Alzheimers

forgetfulness, disorientation, variable mood, restlessness

what are some risk factors

age, family history, ethnicity and genetics

what are the symptoms of mild Alzheimers

gradual memory loss, minor fortgetfulness

what are the symptoms of moderate Alzheimers

confabulation, disorientation, language issues

what are symptoms of severe alzheimers

severe confusion, violent outbursts, incontinence

how is it diagnosed

cognitive testing, physical examinations, lab testing, MRI, CT

what is it associated with

brain shrinkage and loss of neutrons in hippocampus and forebrain

pathophysiology point one

there is a build up of amyloid beta proteins outside the brain

point 2

tau proteins change and forms tangles In brain cells

point 3

these proteins block communication andd trigger inflammation causing apoptosis

point 4

as cells die connections are lost leading to thinking problems

point 5

acetylcholine becomes low

point 6

brain atrophies

what is one of the treatment options

patients have reduced cholingeric activity so therapies are in place to prolong each. cholinesterase inhibitors like galatamine reduce ach break down leading to higher ach levels and improvement in memory