Aluminum Hydroxide Gel

Gels

Suspension, in a water medium of insoluble drugs in hydrated form wherein the particle size approaches or attain colloidal dimension.

Thixotropy

• If undisturbed for some time, they may become semisolid or gelatinous with some small amount of water separating on standing

• If disturbed/shaken/agitated, they liquefy

Very fine particle size

Achieve large surface and thus maximum adsorption capacity

Not exceeding 0.5%

May contain peppermint oil, glycerin, sorbitol, sucrose, saccharin or other suitable flavor and preservative in a total amount.

Jellies

Gels are also called this

Semirigid Systems

Gels are also defined as THIS in which the movement of the dispersing medium is restricted by an interlacing three-dimensional network of particles or solvated macromolecules of the dispersed phase

Inorganic & Organic

Generally, gels list two classification schemes:

Inorganic hydrogels

two-phased systems, such as aluminum hydroxide gel and bentonite magma

Aluminum Hydroxide Gel

Inorganic Hydrogels

Bentonite Magma

Inorganic Hydrogels

Organic gels

single-phased systems and may include gelling agents, such as carbomer and tragacanth

Carbomer

Organic Gels

Tragacanth

Organic Gels

Hot water to Sodium Carbonate

• Form Sodium Hydroxide

• Stir; Release the carbon dioxide upon the reaction.

It produces no systemic alkalosis

Chemical Reaction

Decreases

Absorption of certain drugs like tetracycline

Interferes

Deforming action of simethicone

Sodium benzoate

Preservative

Ammonium alum

Active Ingredient

Sodium carbonate

Reactant

Peppermint oil

Suspending Agent

Purified water

Vehicle

Chelate

Aluminum can form this with other metals and can react with some antibiotics and dairy products because they contain calcium.