LAT 03: Ethics in Animal Research (2021)

LAT

What are the three “R’s”?

• Replacement: Can animals be replaced by non-animal alternatives or less sentient species without interfering with the objectives of the study?

• Reduction: Can fewer animals be used without altering the validity of the study data?

• Refinement: Can the procedures used in the study be refined to lessen pain and distress or minimize the number of potentially painful procedures that the animals must undergo during the study?

Who decides the course of action if an animal exhibits pain and distress before reaching a humane endpoint?

Attending Veterinarian and the Principal Investigator

Why is a study of ethics important for reaching an ethical decision?

To provide a systematic process of ethical decision-making.

Whistleblower protections are required by which regulation or guidelines?

Animal Welfare Regulations and Guide for the Care and Use of Laboratory Animals

What is the goal of ethical decision making in an animal research program?

To balance the consideration of all important factors in the decision.

According to the Guide, _______ means those actions taken to assure that laboratory animals are treated according to high ethical and scientific standards.

humane care

The point at which pain or distress in an experimental animal is prevented, terminated, or relieved is the _________.

humane endpoint

What is the concept that states that people behave based on commonly held core values?

Ethics

What is the definition of compliance?

knowing the rules and following them

What is the name of the policy that an institute has in place to protect individuals who report animal welfare concerns?

Whistleblower policy