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smooth muscle
Intestines/Arteries
Cardiac Muscles
muscles found in the walls of your heart
Muscle Fibers
Bungee cord made of fibers. Activated at the Neuromuscular Junction
Neuromuscular Junction Parts
Axon, Ionotropic Receptors, Synaptic Vescicle, Synaptic Cleft, Muscle Fiber
First step to telling a muscle to move
Brain neurons fire APs
Execution(muscle movement)
Spinal cord motor neurons control muscles. One AP= one contraction
Rubrospinal tract
Red nucleus -> medulla -> spinal cord
NT released with Nocireceptors
Substance P
Spiral Ganglion cells
hand off cells from ear to brain
Dorsal cochlear nucleus auditory pathway
DCN, inferior colliculus, MGN (thalamus), auditory cortex
Vestibular system function
motion, posture, balance, head position, spacial orientation
Semicircular Canals (vestibular system) detects
spinning
Lens
transparent disk that changes shape
Layers of LGN Temporal Retina goes to
2,3,5
Skeletal Muscles
the muscles attached to bones that enable you to move
Neuromuscular Junction
Where a nerve touches a cell
Striations
stripes formed by myofilaments inside myofibrils.
What does Ca2+ do in contractions
moves troponin and tropomysin out of the way
Motor cortex structure
M1, PMA, SMA (Strategy)
Pacinian corpuscle
Largest receptive field, detects vibration on hands
A1 fibers
initial sharp pain, quick adapting
stapes
"stirrup"
Lens shape for close vision
Wide shape
Photoreceptors in Light
Opsin activates, retinal changes shape, Transducin closes Na+ channels and hyperpolarizes the cell
Direction Selectivity
Determines object direction
Second step to telling a muscle to move
travel from the brain, through the spinal cord, to the muscle
third step to telling a muscle to move
axon terminals release acetylcholine at synaptic cleft
fourth step to telling a muscle to move
acetylcholine causes Na+ ion channels to open the muscle
fifth step to telling a muscle to move
Na+ entry causes Ca2+ to enter the muscle cell
sixth step to telling a muscle to move
Ca2+ pushes away the proteins blocking muscle movement
seventh and final step to making a muscle move
Muscle fibers pull each other and shorten the muscle
Myofilaments
Myosin and Actin
Myofibrils/sarcomeres
I-band, A-band and H-band
Sliding filament model
When the troponin/tropomysin are moved and ATP pulls and shortens the sarcomeres.
Lower Motor Neurons use
Commands muscle contraction.
Lower Motor neurons types
Alpha and gamma motor neurons
Alpha motor neurons
Moves powerful fibers, higher firing rate= stronger contractions
Gamma motor neurons
moves less powerful fibers, higher firing rate= stronger contractions
Motor unit
1 alpha neuron and connected fibers
Motor pool
all of the motor neurons that innervate the fibers of a single muscle
Flexors vs extendors
flexors bend limb, extendors extend them
Myotactic Reflex
Causes contraction of a muscle being stretched
Also called stretch reflex
Strategy (muscle movement)
Basal ganglia link reward signals to activities that can obtain rewards
Tactics(muscle movement)
Cerebellum fine-tunes movement with motor cortex. Error correction
Corticospinal Tract
Motor cortex->thalamus->cerebral peduncle->medulla base->Spinal cord
ventromedial pathways control
Balance and posture
The two Lateral Pathways
corticospinal tract and rubrospinal tract
M1
Primary motor pathway
PMA
Premotor area, neurons fire here before movement
SMA
supplemental motor area
Corticostriatal loop
Basal ganglia -> thalamus -> premotor cortex (choosing an action)
Basal Ganglia loop
Cerebral cortex -> striatum -> Globus pallidus -> thalamus
Corticocerebellar loop
Cerebellum -> thalamus -> primary motor cortex
Corticocerebellar loop job
Refines movement
Epidermis
Outer, dry, protective skin layer
Dermis
inner skin layer with nerves and blood vessels
Skin Mechanoreceptors activation
Activated by stretching or cell movement of actin
Merkel's disk
Slow adapting (generate a sustained AP frequency)
Meissner's corpuscle
on fingers, small receptive field, fine tuned movement
Corpuscles
Fire rapidle, quick adapting
C fibers
lasting dull pain, slow adapting
Dermatomes
Spinal Segments
Medial Lemniscal Pathway
Dorsal column, medial lemniscus (medulla), thalamus, S1
Medial Lemnsical pathway function
Touch/vibration
Trigeminal Touch pathway
Pons, thalamus, S1
Trigeminal touch pathway function
Moving face (cranial nerves)
Nocireceptors
Pain receptors
Mast Cell function
release histamine
Prostoglandins function
indicates cell death
Spinothalamic pathway
Spinal cord, medulla, thalamus, S1
TRP Channels
Channels that register temperature
TRPV1
The TRP channel hot peppers bind to
Frequency
the number of complete wavelengths that pass a point in a given time
Intensity
Air pressure
Pinna
The visible ear
Auditory Canal
entrance to the ear
tympanic membrane
the ear drum
malleus
"hammer"
incus
"anvil"
The three ossicle bones
malleus, incus, stapes
Footplate
Bottom of stapes, moves oval window
Oval window
membrane that leads from middle ear to inner ear
cochlea
snail-shaped structure of the inner ear that is filled with fluid
Organ of corti
Center part of the cochlea, containing hair cells, canals, and membranes
Scala media
Middle chamber of the cochlea; filled with endolymph (has organ of corti in it)
three fluid filled chambers of the cochlea
Scala media, scala vestibuli, scala tympani
Auditory vestibular nerve
Cranial nerve VIII, consisting of axons projecting from the spiral ganglion to the cochlear nuclei
Eustachian Tube
nasal cavity connection to middle ear
Stereocilia
hairlike extensions on the tips of hair cells in the cochlea that initiate the release of neurotransmitters when they are flexed
Depolarization of stereocilia
Endolymph bends stereocilia, K+ goes in, Ca2+ goes in, glutamate is released activating spiral ganglion cells
ventral cochlear nucleus auditory pathway
VCN, superior olive, inferior colliculus, MGN (thalamus), auditory cortex
Phase locking
the consistent firing of an auditory neuron at the same phase of a sound wave
Tonotopy
spatial arrangement of where sounds of different frequency are processed in the brain
Interaural time delay
time taken for sound to reach from ear to ear
otolith organs function
forward, back, left, right
Otolith organs
Otoconia, Kinocillium
Otoconia
calcium carbonate crystals that move in direction with you
Kinocillium
Tallest sterocilium of the hair cell
Semicircular canals (vestibular system)
The three hollowed tubes in the inner ear filled with endolymph. Has clustered hair cells
Cornea
External surface of eye