Transplantation Lecture Flashcards

Flashcards on Transplantation Lecture

Donor

The person donating the organ or tissue.

Recipient

The person receiving the organ or tissue transplant.

Allograft

Transfer of organ or tissues between genetically different individuals.

Xenograft

Transplanted tissue from another species.

MHC molecules

Also known as human leukocyte antigen, these are antigen presenting molecules.

HLA antigens

MHC molecules in humans.

HLA haplotype

The inherited package of HLA genes from each parent.

Hyperacute rejection

Occurs within minutes to hours of a transplant due to pre-existing antibodies.

Acute rejection

Occurs within days or weeks of a transplant, mainly mediated by T cells.

Chronic rejection

Slow form of graft rejection occurring over months or years, mediated by CD4 T cells and antibodies.