transcription factors and problems with doping
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Last updated 10:33 AM on 6/9/23
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12 Terms
1
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what are transcription factors
proteins that bind to specific base sequences that either stimulate or prevent transcription of a gene
2
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where is a premotor sequence found
upstream of a gene they act on
3
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what do premotor sequences enable
binding of rna polymerase and therefore promote transcription
4
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how do enhancer sequences work
regulate dna activity by changing chromatin structure changing how easy it is to open rna polymerase
5
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what is the effect of chromatin opening rna polymerase
active gene expression
6
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what is an example of a steroid hormone
testosterone
7
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how do steroid hormones initiate a change
* enter through plasma membrane forming hormone-receptor complex
* this initiates a change in the nucleus
* this initiates a change in the nucleus
8
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what is an example of a peptide hormone
EPO
9
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whats the difference between steroid and peptide hormones
steroid hormones are lipid soluble, peptide are not.
10
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how do peptide hormones bring about a change
cant enter the cell so they release a secondary messenger molecule from the cell membrane which enters the nucleus
11
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why may doping be acceptable
athletes have the right to decide for themselves
may allow disadvantaged to compete at a higher level w
may allow disadvantaged to compete at a higher level w
12
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why is doping not acceptable
athletes don’t always know the risks
makes competition unfair
makes competition unfair
Note 
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