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What type of virus is distemper
Enveloped RNA virus
CDV envelope spike proteins
Hemagglutinin and neuraminidase
CDV trasmission
Depends on strain; commonly respiratory or fecal
Site of CDV primary replication
Macrophages in oropharynx
What determines severity oo disease seen with CDV
Immune response
How does CDV affect multiple systems
It is pantropic, and can infect cells in many different organs
Subclinical CDV
Strong immune response → mild respiratory disease → clears and recovers