Organic Chemistry Carbonyl pKas
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Typical acidities of carbonyl compounds (measured by pKa values of alpha hydrogens). From Organic Chemistry, 9th Ed. (Wade & Simek)
Last updated 2:46 AM on 4/13/25
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14 Terms
1
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Acetone
pKa 20
2
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Ethyl acetate
pKa 24
3
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beta Diketone
pKa 9
4
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beta Keto ester
pKa 11
5
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beta Diester
pKa 13
6
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water
pKa 15.7
7
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methanol
pKa 15.5
8
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ethanol
pKa 15.9
9
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nitrile
pKa 25
10
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nitro
pKa 10
11
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beta Keto nitrile
pKa 12
12
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alpha Nitro ketone
13
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phenol
pKa 10
14
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ammonium ion
pKa 9.2
Note 
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