Electron Transport

Oxygen is essential in cellular respiration —

To make a good amount of ATP

Lethal Metabolic Poison-

Cyanide (CN)

Dinitrophenol — ATP sequence

disrupts the electron transport chain, leading to decreased ATP production.

ATP molecules are made — during cellular respirations

Mitochondria

Where can the Electron Transport chain is found?

In the inner mitochondrial membrane.

What energy-rich molecules supply ETC with energy rich electrons

NADH and FADH2

The flow of H + ions through the channel portion of the — activates it catalytic activity to synthesize ATP

ATP synthase enzyme

Cyanide is lethal because it — ATP synthesis in the —-

Stop: Mitochondrion

Electron exchange is like an

Electrical current (Electricity)

NADH and FADH2 supply Energy-Rich electrons to the

Elecrons Transport chain (ETC)

How is NADH and FADH2 made?

• Energy in food molecules

Hydrogen Ion concentration gradient across the inner mitochondrial membrane energizes the —

ATP Synthase Enzyme

Inner Mitochondrial membrane contains Many —

ATP synthase Enzymes

What is ATP synthase enzymes?

They are enzymes located in the inner mitochondrial membrane that synthesize ATP from ADP and inorganic phosphate, utilizing the energy from the hydrogen ion concentration gradient.

ATP synthase enzymes consist of — parts

TWO main parts: F0 and F1 domains.

What are the two main parts of ATP synthase enzymes

F0 and F1 domains.

The — part in the inner Mitochondrial membrane is the channel portion through which H+ ions diffuse

F0 domain

The — part is the catalytic subunit whose active site add PO4 (Pi) to ADP to make ATP

F1 domain

ATP molecules made in the mitochondria must be — to the — to supply cell with —

Exported; Cytosol; energy

What transports ATP across the inner mitochondrial membrane during ETC?

Adenine nucleotide translocase (ANT)

Adenine nucleotide translocase (ANT) is — in the inner membrane

a protein

Total ATP production during cellular respiration

up to 38 ATP molecules

2 NADH from glycolysis produce how many APT during cellular respiration

approximately 5 ATP molecules

2 NADH from Pyruvate produce how many APT during cellular respiration

approximately 6 ATP molecules

6 NADH from Krebs cycle produce how many APT during cellular respiration

approximately 18 ATP molecules

2 FADH2 in Krebs cycle produce how many APT during cellular respiration

approximately 4 ATP molecules

During Cellular respiration, Glycolysis Results — ATP Per Glucose Molecule

In 7-8

During Cellular respiration, Pyruvate Oxidation Results— Per Glucose Molecule

In 5-6 ATP

During Cellular respiration, Krebs Cycle Results — Per Glucose Molecule

In 20-24 ATP

— require O2 to perform cellular respiration

Aerobic Species ( pathways) that produce energy.

— uses electrons from the ETC to covert O2 to water to enable electron flow

Cytochrome c oxidase enzyme complex

— is a lethal metabolic poison that inhibits the Cytochrome c oxidase enzyme complex in the ETC.

Cyanide (CN)

Cyanide (CN) inhibit Cytochrome C Oxidase To Eliminate

• Electron flow through the ETC

• ATP synthesis by ATP Synthase

• H+ Ion concentration Gradient formation

Dinitrophenol (DNP) — ATP Synthesis

Reduces

Dinitrophenol (DNP) also reduces the — of H+ Ion Concentration Gradient

ability to create (Magnitude)

— reduces the number of hydrogen ion available to activate ATP synthase

Dinitrophenol (DNP) reduces the number of hydrogen ions available to activate ATP synthase.

However, a safe doses of DNP help in

Treatments for Metabolic syndrome, Neurodegenerative disorders (Alzheimer’s, HD, MS, Parkinson’s) and Obesity.

ATP molecules made in Mitochondria must be exported to the — to supply cells wit energy.

Cytosol

Adenine Nucleotide Translocator (ANT) transport —- across the inner mitochondrial membrane to the cytosol

ATP

ANT is a — in the inner membrane

Protein